Objective Dietary methionine restriction (MR) reduces adiposity and hepatic lipids and
increases overall insulin sensitivity in part by reducing lipogenic gene expression in liver …

Metformin (MET) has been demonstrated to have favorable impact on nonalcoholic fatty liver
disease (NAFLD); however, the combined effect of this drug with p-coumaric acid (PCA) on …

Excessive fat accumulation in broiler chickens would seriously threaten the poultry industry.
It leads to lower feed conversion rate and worse meat quality. Even worse, it harms the …

Ectopic lipid accumulation in skeletal muscle and liver arises when nutrient storage systems
are exposed to chronic energy surplus, leading to whole-body insulin resistance and …

The polyamine spermidine is discussed as a caloric restriction mimetic and therapeutic
option for obesity and related comorbidities. This study tested oral spermidine …

Background/Aims: Fisetin is a naturally abundant flavonoid isolated from various fruits and
vegetables that was recently identified to have potential biological functions in improving …

Effective and safe pharmacological interventions for hyperlipidemia remains badly needed.
By incorporating the key pharmacophore of fibrates into the natural scaffold of resveratrol, a …

D-pinitol is one of the major inositol found in plants and studies suggest its potential
hypoglycemic and hypolipidemic actions in diabetic rodents. Here, we investigated the …

Lipogenesis is the process by which fatty acids are synthesized. In metabolic syndrome, an
insulin resistant state along with high plasma levels of free fatty acids (FFA) and …

Tomatidine is isolated from the leaves and green fruits of some plants in the Solanaceae
family, and has been reported to have anti-inflammatory and antitumor effects. Previous …