D-pinitol is one of the major inositol found in plants and studies suggest its potential
hypoglycemic and hypolipidemic actions in diabetic rodents. Here, we investigated the …

Weight loss is recommended for patients with nonalcoholic fatty liver disease (NAFLD),
while metformin may lower liver enzymes in type 2 diabetics. Yet, the efficacy of the …

Tomatidine is isolated from the leaves and green fruits of some plants in the Solanaceae
family, and has been reported to have anti-inflammatory and antitumor effects. Previous …

Nicotinamide riboside, an NAD+ precursor, has been attracting a lot of attention in recent
years due to its potential benefits against multiple metabolic complications and age-related …

Several in vitro and in vivo studies have reported the anti-inflammatory, anti-diabetic and
anti-obesity effects of the flavonoid apigenin. However, the long-term supplementary effects …

The increasing global prevalence of nonalcoholic fatty liver disease (NAFLD) starves for
effective therapy, but no agent has been approved yet. We sought to evaluate the therapy of …

Morin is a natural bioflavonoid that exhibits antioxidant and anti-inflammatory properties.
The present study was designed to evaluate the effect of morin on insulin resistance …

Although many clinical trials have showed that metformin improves non-alcoholic fatty liver
disease, which is a common liver disease associated with hepatic enzyme abnormalities, an …

Abstract Background/Aims: Methionine restriction (MR) is a dietary intervention that
increases lifespan, reduces adiposity and improves insulin sensitivity. These effects are …

Chronic administration of sibutramine lowers body weight, presumably by altering brain
monoamine metabolism. Here the effect of sibutramine on sympathoadrenal function (24-h …