Rational and Evolutionary Engineering Approaches Uncover a Small Set of Genetic Changes Efficient for Rapid Xylose Fermentation in Saccharomyces cerevisiae

SR Kim, JM Skerker, W Kang, A Lesmana, N Wei… - PloS one, 2013 - journals.plos.org
Economic bioconversion of plant cell wall hydrolysates into fuels and chemicals has been
hampered mainly due to the inability of microorganisms to efficiently co-ferment pentose and …

Establishment of a carbon-efficient xylulose cleavage pathway in Escherichia coli to metabolize xylose

LL Shi, Y Zheng, BW Tan, ZJ Li - Biochemical Engineering Journal, 2022 - Elsevier
As the second-largest storage saccharide in the world, xylose is a promising renewable
feedstock in the bio-industry. A few microorganisms can metabolize xylose naturally via the …

Advances in applications, metabolism, and biotechnological production of L-xylulose

Q Meng, T Zhang, B Jiang, W Mu, M Miao - Applied microbiology and …, 2016 - Springer
L-Xylulose is an intermediate in certain metabolic pathways and is classified as a rare sugar.
It shows important physiological effects such as acting as an inhibitor of α-glucosidase and …

Production of L-xylulose from xylitol by a newly isolated strain of Bacillus pallidus Y25 and characterization of its relevant enzyme xylitol dehydrogenase

W Poonperm, G Takata, K Morimoto… - Enzyme and microbial …, 2007 - Elsevier
A novel facultative thermophilic bacterium capable of producing rare ketoses from polyols
was isolated from soil and identified as Bacillus pallidus Y25. We have employed this …

Engineering of Corynebacterium glutamicum for xylitol production from lignocellulosic pentose sugars

KS Dhar, VF Wendisch, KM Nampoothiri - Journal of biotechnology, 2016 - Elsevier
Xylitol is a non-fermentable sugar alcohol used as sweetener. Corynebacterium glutamicum
ATCC13032 was metabolically engineered for xylitol production from the lignocellulosic …

Microbial conversion of xylose into useful bioproducts

SS Jagtap, CV Rao - Applied microbiology and biotechnology, 2018 - Springer
Microorganisms can produce a number of different bioproducts from the sugars in plant
biomass. One challenge is devising processes that utilize all of the sugars in lignocellulosic …

Directed evolution and secretory expression of xylose isomerase for improved utilisation of xylose in Saccharomyces cerevisiae

JH Bae, MJ Kim, BH Sung, YS Jin, JH Sohn - Biotechnology for Biofuels, 2021 - Springer
Background Xylose contained in lignocellulosic biomass is an attractive carbon substrate for
economically viable conversion to bioethanol. Extensive research has been conducted on …

Process development for crystalline xylitol production from corncob biomass by Pichia caribbica

D Dasgupta, A Sidana, B Sarkar, S More… - Food and Bioproducts …, 2022 - Elsevier
Xylitol, a commodity chemical, is widely used in nutraceutical and pharmaceutical
formulations. Microbial xylitol production is a promising alternative to mitigate current …

Engineering of xylose metabolism in Escherichia coli for the production of valuable compounds

AB Bañares, GM Nisola, KNG Valdehuesa… - Critical Reviews in …, 2021 - Taylor & Francis
The lignocellulosic sugar d-xylose has recently gained prominence as an inexpensive
alternative substrate for the production of value-added compounds using genetically …

Production of xylitol by expressing xylitol dehydrogenase and alcohol dehydrogenase from Gluconobacter thailandicus and co-biotransformation of whole cells

H Zhang, J Yun, H Zabed, M Yang, G Zhang, Y Qi… - Bioresource …, 2018 - Elsevier
In the present study, recombinant strains were constructed for xylitol production by cloning
and expressing the novel xylitol dehydrogenase (xdh) and alcohol dehydrogenase (adh) …