Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae

K Karhumaa, RG Sanchez, B Hahn-Hägerdal… - Microbial cell …, 2007 - Springer
Background Two heterologous pathways have been used to construct recombinant xylose-
fermenting Saccharomyces cerevisiae strains: i) the xylose reductase (XR) and xylitol …

Directed evolution of xylose isomerase for improved xylose catabolism and fermentation in the yeast Saccharomyces cerevisiae

SM Lee, T Jellison, HS Alper - Applied and Environmental …, 2012 - Am Soc Microbiol
The heterologous expression of a highly functional xylose isomerase pathway in
Saccharomyces cerevisiae would have significant advantages for ethanol yield, since the …

Processes of fermentative production of xylitol—a sugar substitute

P Nigam, D Singh - Process Biochemistry, 1995 - Elsevier
Agricultural residues rich in carbohydrate content, such as hemicellulose, are produced in
large amounts annually world-wide. These biological byproducts, which are wastes, can be …

Engineering xylose metabolism in yeasts to produce biofuels and chemicals

JW Lee, S Yook, H Koh, CV Rao, YS Jin - Current Opinion in Biotechnology, 2021 - Elsevier
Xylose is the second most abundant sugar in lignocellulosic biomass. Efficient and rapid
xylose utilization is essential for the economic bioconversion of lignocellulosic biomass into …

Xylitol as bioproduct from the agro and forest biorefinery

ME Vallejos, MC Area - Food Bioconversion, 2017 - Elsevier
Xylans from hemicelluloses can be depolymerized into xylose for the bioproduction of xylitol.
Xylitol is used as a sweetening agent, and it can be an important platform for sustainable …

Xylose fermentation by Saccharomyces cerevisiae using endogenous xylose-assimilating genes

J Konishi, A Fukuda, K Mutaguchi, T Uemura - Biotechnology letters, 2015 - Springer
Abstract Objectives To genetically engineer Saccharomyces cerevisiae for improved ethanol
productivity from glucose/xylose mixtures. Results An endogenous gene cassette composed …

Development of Efficient Xylose Fermentation in Saccharomyces cerevisiae: Xylose Isomerase as a Key Component

AJA Van Maris, AA Winkler, M Kuyper, WTAM De Laat… - Biofuels, 2007 - Springer
Metabolic engineering of Saccharomyces cerevisiae for ethanol production from d-xylose,
an abundant sugar in plant biomass hydrolysates, has been pursued vigorously for the past …

Toward rapid and efficient utilization of nonconventional substrates by nonconventional yeast strains

HG Koh, S Yook, H Oh, CV Rao, YS Jin - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•The potential of Y. lipolytica and R. toruloides for xylose and acetate
utilization.•Intense multi-omics analysis has been carried out under xylose/acetate …

Microbial production of xylitol from L-arabinose by metabolically engineered Escherichia coli

Y Sakakibara, BC Saha, P Taylor - Journal of bioscience and …, 2009 - Elsevier
An Escherichia coli strain, ZUC99 (pATX210), which can produce xylitol from l-arabinose at
a high yield, has been created by introducing a new bioconversion pathway into the cells …

Microbial production of xylitol from oil palm empty fruit bunches hydrolysate: The effect of glucose concentration

E Mardawati, DW WIRA, M Kresnowati… - Journal of the Japan …, 2015 - jstage.jst.go.jp
1. Introduction Xylitol is a polyalcoholic sugar with five carbon atoms which is found naturally
in fruits and vegetables albeit in small quantity. Xylitol has similiar sweetness to sucrose, but …