[HTML][HTML] Minimal residual disease in acute lymphoblastic leukemia: technical and clinical advances
I Della Starza, S Chiaretti, MS De Propris, L Elia… - Frontiers in …, 2019 - frontiersin.org
… residual leukemic cells in ALL patients. The advent of novel techniques, namely next
generation flow cytometry (NGF), digital-droplet-PCR (ddPCR), and next generation sequencing (…
generation flow cytometry (NGF), digital-droplet-PCR (ddPCR), and next generation sequencing (…
Association of measurable residual disease with survival outcomes in patients with acute myeloid leukemia: a systematic review and meta-analysis
… Study Group for Adult Acute Lymphoblastic Leukemia. Clinical significance of minimal residual
disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. …
disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. …
[HTML][HTML] Minimal residual disease detection in acute lymphoblastic leukemia
A Kruse, N Abdel-Azim, HN Kim, Y Ruan… - International journal of …, 2020 - mdpi.com
… (which may include allogeneic stem cell transplantation) and to create risk profiles for
patients based on measured clearance of leukemic cells and post-treatment probability of …
patients based on measured clearance of leukemic cells and post-treatment probability of …
Minimal residual disease and survival outcomes in patients with chronic lymphocytic leukemia: a systematic review and meta-analysis
S Molica, D Giannarelli, E Montserrat - … Lymphoma Myeloma and Leukemia, 2019 - Elsevier
… Patients with chronic lymphocytic leukemia (CLL) who achieve undetectable minimal residual
disease (U-MRD) (ie, < 10 -4 detectable leukemic cells in peripheral blood or bone marrow…
disease (U-MRD) (ie, < 10 -4 detectable leukemic cells in peripheral blood or bone marrow…
Measurable residual disease as a biomarker in acute myeloid leukemia: theoretical and practical considerations
… ”) residual disease (MRD) in acute myeloid leukemia (AML). Although the perfect MRD test
does not (yet) exist, the strong association between MRD and adverse patient outcomes has …
does not (yet) exist, the strong association between MRD and adverse patient outcomes has …
[HTML][HTML] Minimal residual disease in acute lymphoblastic leukemia: current practice and future directions
GP Contreras Yametti, TH Ostrow, S Jasinski, EA Raetz… - Cancers, 2021 - mdpi.com
… Residual Disease The rate at which ALL regresses after initiation of induction therapy varies
from patient to patient… Overall, patients with higher residual disease following treatment have …
from patient to patient… Overall, patients with higher residual disease following treatment have …
[HTML][HTML] Minimal residual disease in chronic lymphocytic leukemia: a new goal?
I Del Giudice, S Raponi, I Della Starza… - Frontiers in …, 2019 - frontiersin.org
… chemotherapy (FC or Chl or B) in TN or R/R CLL patients, a subgroup analysis of 158 TN
CLL patients receiving B+G was reported. ORR was 81.0%, with uMRD in 59.5% and 27.8% of …
CLL patients receiving B+G was reported. ORR was 81.0%, with uMRD in 59.5% and 27.8% of …
[HTML][HTML] Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations
WG Wierda, A Rawstron, F Cymbalista, X Badoux… - Leukemia, 2021 - nature.com
… assessment improves prediction of outcome in patients with chronic lymphocytic leukemia
(CLL) who achieve partial response: comprehensive analysis of two-phase III studies of the …
(CLL) who achieve partial response: comprehensive analysis of two-phase III studies of the …
Clonal hematopoiesis and measurable residual disease assessment in acute myeloid leukemia
RP Hasserjian, DP Steensma… - Blood, The Journal …, 2020 - ashpublications.org
… CH detected in AML patients in CR includes true residual or early recurrent AML,
myelodysplastic syndrome or CH that is ancestral to the AML, and independent or newly emerging …
myelodysplastic syndrome or CH that is ancestral to the AML, and independent or newly emerging …
[HTML][HTML] Prognostic and therapeutic implications of measurable residual disease in acute myeloid leukemia
MJL Aitken, F Ravandi, KP Patel, NJ Short - Journal of Hematology & …, 2021 - Springer
… patients found better CIR and OS in patients with undetectable mutations compared with
those with residual … (482 patients, 54 genes), presence of any non-DTA leukemia-associated …
those with residual … (482 patients, 54 genes), presence of any non-DTA leukemia-associated …
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