Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis
C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
… their circulation aggravates the delayed apoptosis 25 . Thus the inhibition of neutrophil
apoptosis in sepsis could be harmful to host immunity, and neutrophil infiltration into tissues could …
apoptosis in sepsis could be harmful to host immunity, and neutrophil infiltration into tissues could …
Dysregulation of neutrophil death in sepsis
C Zhu, Y Wang, Q Liu, H Li, C Yu, P Li, X Deng… - Frontiers in …, 2022 - frontiersin.org
… We and others found that neutrophil apoptosis was significantly reduced in patients with …
neutrophil apoptosis in patients with sepsis showed that the mechanism of delayed apoptosis …
neutrophil apoptosis in patients with sepsis showed that the mechanism of delayed apoptosis …
The critical roles and mechanisms of immune cell death in sepsis
Z Cheng, ST Abrams, J Toh, SS Wang, Z Wang… - Frontiers in …, 2020 - frontiersin.org
… Neutrophil respiratory burst and NETosis all … neutrophil apoptosis occurs via cIAP-2 activation
and the degradation of caspase-3 (68). The detailed molecular mechanisms of neutrophil …
and the degradation of caspase-3 (68). The detailed molecular mechanisms of neutrophil …
[HTML][HTML] Neutrophil activity in sepsis: a systematic review
CB Resende, I Borges, WA Gonçalves… - Brazilian Journal of …, 2020 - SciELO Brasil
… The occurrence of neutrophil apoptosis in sepsis was investigated in five (26%) of the studies
included in this review. In all of those studies, the authors observed reduced expression of …
included in this review. In all of those studies, the authors observed reduced expression of …
Immune profile of patients‑a new approach in management of sepsis and septic shock?
… circulating factor in severe sepsis/shock modulates the apoptosis of CD4+ lymphocytes and
… delayed apoptosis of circulating neutrophils (33). In the present study the neutrophil count at …
… delayed apoptosis of circulating neutrophils (33). In the present study the neutrophil count at …
Apoptotic cell therapy for cytokine storm associated with acute severe sepsis
N Karbian, A Abutbul, R El-Amore, R Eliaz… - Cell Death & …, 2020 - nature.com
… Apoptotic cell administration markedly improved the cytokine … and glycolytic function in white
blood cells leading to increased … -induced sepsis can be successfully modified by apoptotic …
blood cells leading to increased … -induced sepsis can be successfully modified by apoptotic …
Upregulated PD-L1 delays human neutrophil apoptosis and promotes lung injury in an experimental mouse model of sepsis
J Wang, Y Wang, J Xie, Z Zhao, S Gupta… - Blood, The Journal …, 2021 - ashpublications.org
… with sepsis-induced immunosuppression. Other work has shown that neutrophil apoptosis
is … We therefore sought to investigate whether PD-L1 delays ex vivo neutrophil apoptosis by …
is … We therefore sought to investigate whether PD-L1 delays ex vivo neutrophil apoptosis by …
Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou… - Scientific reports, 2019 - nature.com
… Cell surface expression of intermediate filament proteins vimentin and lamin B1 in
human neutrophil spontaneous apoptosis. J Leukoc Biol 79, 489–498, https://doi.org/10.1189/jlb.…
human neutrophil spontaneous apoptosis. J Leukoc Biol 79, 489–498, https://doi.org/10.1189/jlb.…
Inflammation and cell death of the innate and adaptive immune system during sepsis
C Nedeva - Biomolecules, 2021 - mdpi.com
… Additionally, reduced expression of human leukocyte antigen, HLA-DR, is associated with
… Most importantly, the increase in apoptosis of NK cells during sepsis leads to a decrease in …
… Most importantly, the increase in apoptosis of NK cells during sepsis leads to a decrease in …
Emerging mechanisms of immunocoagulation in sepsis and septic shock
… of sepsis in 1991 (Sepsis 1.0) and 2001 (Sepsis 2.0). The Sepsis 3.0 consensus abandons
the concept of sepsis as a systemic inflammatory response syndrome (SIRS) due to infection, …
the concept of sepsis as a systemic inflammatory response syndrome (SIRS) due to infection, …
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