Biological signatures of Alzheimer's disease
P Sharma, A Sharma, F Fayaz… - Current Topics in …, 2020 - ingentaconnect.com
… If the current trend continues, the cases of Alzheimer's disease will increase four times in the
… distribution of the pathological changes in the neocortex in alzheimer disease. Proc. Natl. …
… distribution of the pathological changes in the neocortex in alzheimer disease. Proc. Natl. …
[HTML][HTML] Using path signatures to predict a diagnosis of Alzheimer's disease
…, Alzheimer's Disease Neuroimaging Initiative - PloS one, 2019 - journals.plos.org
… , the phase of MCI ends with a marked decline in cognitive function as the disease pathology
… Is the Subject Area "Alzheimer's disease diagnosis and management" applicable to this …
… Is the Subject Area "Alzheimer's disease diagnosis and management" applicable to this …
[HTML][HTML] Biomarker-based signature of Alzheimer's disease in pre-MCI individuals
E Chipi, N Salvadori, L Farotti, L Parnetti - Brain Sciences, 2019 - mdpi.com
… Structural abnormalities in these regions represent a marker of AD pathology, so-called “AD-signature”
[134,135]. The regions have been previously described as the Default Mode …
[134,135]. The regions have been previously described as the Default Mode …
Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease
… tau pathology at different stages of AD. Although we identified commonly regulated proteins
and pathways during disease … In addition, a distinct proteomic signature was found between …
and pathways during disease … In addition, a distinct proteomic signature was found between …
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease
… decline in Alzheimer’s disease (AD). However, the molecular signatures that distinguish …
identified both shared and cell-type-specific signatures. NFT-bearing neurons shared a marked …
identified both shared and cell-type-specific signatures. NFT-bearing neurons shared a marked …
[HTML][HTML] Retinal pathological features and proteome signatures of Alzheimer's disease
… disease progression in the brain remain largely unknown. To better understand the pathological
… , and atrophy correlated with severity of brain Aβ pathology, tauopathy, and atrophy, and …
… , and atrophy correlated with severity of brain Aβ pathology, tauopathy, and atrophy, and …
[HTML][HTML] Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease
… a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD)
pathology … Since late-onset Alzheimer disease (LOAD) participants tend to have age-related …
pathology … Since late-onset Alzheimer disease (LOAD) participants tend to have age-related …
Brain metabolic signatures across the Alzheimer's disease spectrum
A Sala, C Caprioglio, R Santangelo, EG Vanoli… - European journal of …, 2020 - Springer
… We identified hypometabolism signatures for each clinical atypical variant within the AD …
paradigm of neurodegenerative disease, positing that the pathology associated with these …
paradigm of neurodegenerative disease, positing that the pathology associated with these …
A machine learning approach to identify a circulating MicroRNA signature for Alzheimer disease
X Zhao, J Kang, V Svetnik, D Warden… - The journal of …, 2020 - academic.oup.com
… Alzheimer disease (AD) diagnosis. Our results indicate that the serum microRNA signature
… Alzheimer disease (AD) 6 is the most common form of dementia with increasing prevalence …
… Alzheimer disease (AD) 6 is the most common form of dementia with increasing prevalence …
A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets
… signature. In steps 3 and 4, we tested associations between the incipient AD proteomic
signature and both AD pathology … pathology. In step 6b, we validated the incipient AD proteomic …
signature and both AD pathology … pathology. In step 6b, we validated the incipient AD proteomic …
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