… protein structures simultaneously by iterative conformational sampling, unlike GalaxyRefine,
which was limited to local refinement… (18) and CASP13 refinement experiments. This server …

… The amino acid sequence and a 3D model (in Protein Data Bank (PDB) format) of the target
are the only required inputs to refine protein structures and the method has recently been …

… to fully establish the structure of a protein. These data are … the structure, but are also often
simultaneously ambiguous (not … to refine the structures of both soluble and membrane proteins …

… refine protein structures based on their secondary structures and torsion angles. The process
begins by identifying inconsistent local structures … : simultaneous refinement of inaccurate …

… Critical Assessment of Structure Prediction refinement targets, our … Our method may refine
one protein model within ~11 min on … the global lDDT and residue-wise lDDT simultaneously. …

… successful refinement protocols in the recent blind 13th Critical Assessment of Structure …
Rosetta based protein structure refinement. Our approach is schematically outlined in Fig. 1. …

… refinement algorithms often systematically under-fit and over-fit different regions of a 3D
structure simultaneously. This causes a loss of resolvable detail in some parts of a structure and …

… It is therefore fair to say that no available cryo-EM refinement method simultaneously meets
… automated yet accurate method for structure refinement and validation, denoted correlation-…

Ensemble refinement produces structural ensembles of flexible and dynamic biomolecules
by integrating experimental data and molecular simulations. Here we present two efficient …

… and side chain refinement. For 3 or more domain assemblies, a global structural refinement
… If we simply implement the CL and cryo-EM restraints simultaneously, the model quality can …