Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… of this study To our knowledge, this is the first phase 3 study to compare the efficacy of erlotinib
… These data indicate that the safety profiles of erlotinib plus bevacizumab in this study and …

Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… using the International Association for the Study of Lung Cancer 7th edition staging system
(… The median PFS observed in the erlotinib arm in our study is similar to the median PFS …

[HTML][HTML] A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

P Thomas, B Vincent, C George… - … of Medical Research, 2019 - journals.lww.com
study showed that erlotinib and gefitinib had similar effectiveness but gefitinib had a better
safety profile compared to erlotinib… for NSCLC patients compared to erlotinib. However, further …

Bevacizumab plus erlotinib versus erlotinib alone in Japanese patients with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival …

Y Kawashima, T Fukuhara, H Saito… - The Lancet …, 2022 - thelancet.com
… To our knowledge, our study is the only phase 3 study to … phase 3 study comparing
bevacizumab–erlotinib with erlotinib alone … The overall survival results from these studies will help …

[HTML][HTML] Erlotinib plus bevacizumab vs erlotinib monotherapy as first-line treatment for advanced EGFR mutation-positive non-squamous non-small-cell lung cancer …

N Yamamoto, T Seto, M Nishio, K Goto, I Okamoto… - Lung Cancer, 2021 - Elsevier
… Firstly, our study enrolled only Japanese patients, therefore we await the results of other
randomized studies with patients treated with the combination of erlotinib plus bevacizumab in …

Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
study of erlotinib and its … study assessing low-dose erlotinib in elderly or frail patients with
EGFR mutation–positive NSCLC. We verified the clinical efficacy of low-dose erlotinib in these …

Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer

B Vaidya, V Parvathaneni, NS Kulkarni… - International journal of …, 2019 - Elsevier
… of the study was to increase the efficacy of erlotinib against erlotinib-resistant non-small cell
lung cancer… For this purpose, cytotoxicity of developed NPs was evaluated in both erlotinib

[HTML][HTML] SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer

NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
… within the first month of treatment because of intolerance, whereas four patients
continued erlotinib beyond 2 years (off study) because of patient or physician preference. …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… , and erlotinib are recommended … study is to investigate how afatinib is used in real-world
practice, and whether it leads to different clinical outcomes compared with gefitinib or erlotinib

Click ferrocenyl-erlotinib conjugates active against erlotinib-resistant non-small cell lung cancer cells in vitro

P Biegański, M Godel, C Riganti, DF Kawano… - Bioorganic …, 2022 - Elsevier
… However, erlotinib-resistant lung cancer remains an unsolved … of erlotinib together with
their anticancer activity studies against erlotinib-sensitive A549 and H1395 as well as erlotinib-…