Disparities and trends in genetic testing and erlotinib treatment among metastatic non–small cell lung cancer patients
LL Palazzo, DF Sheehan, AC Tramontano… - Cancer Epidemiology …, 2019 - AACR
… with erlotinib, which accounted for over 98% of lung cancer … least one prescription with a
generic name of “Erlotinib HCL.” … in NSCLC was continually developing over our study time …
generic name of “Erlotinib HCL.” … in NSCLC was continually developing over our study time …
[HTML][HTML] … versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung: Final analysis of the randomised phase 3 LUX-Lung …
… 8 was originally published, data from this study suggest that patients with ERBB mutations
are … is the second most common histological subtype of non-small cell lung cancer (NSCLC) …
are … is the second most common histological subtype of non-small cell lung cancer (NSCLC) …
Incidence of T790M in patients with NSCLC progressed to gefitinib, erlotinib, and afatinib: a study on circulating cell-free DNA
… or erlotinib. The incidence of T790M in the gefitinib/erlotinib cohort in the present study was
… by the anatomic location and tumor volume. Comparing the T790M positivity of the present …
… by the anatomic location and tumor volume. Comparing the T790M positivity of the present …
[HTML][HTML] Erlotinib as standard adjuvant therapy for resectable EGFR mutation-positive non-small cell lung cancer
S Tanaka, J Uchino - Translational Lung Cancer Research, 2019 - ncbi.nlm.nih.gov
… also caused ILD in 4.6% of Japanese patients in phase II studies (11-13). In this study, severe
ILD was reported in 1 of the 50 patients in the erlotinib group; although the incidence was …
ILD was reported in 1 of the 50 patients in the erlotinib group; although the incidence was …
Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-small-cell lung cancer: a systematic review and meta-analysis of …
W Deng, K Wang, Y Jiang, D Li, C Bao, J Luo, L Liu… - BMJ open, 2022 - bmjopen.bmj.com
… This study aimed to investigate the efficacy and safety of erlotinib plus … In this study, we
compared patient groups treated with erlotinib plus bevacizumab with those treated with erlotinib …
compared patient groups treated with erlotinib plus bevacizumab with those treated with erlotinib …
[HTML][HTML] β-elemene enhances the antitumor activity of erlotinib by inducing apoptosis through AMPK and MAPK pathways in TKI-resistant H1975 lung cancer cells
… In this study, the NCI-H1975 cell line harboring double … study only studied the synergistic
effect of β-elemene on the antitumor activity of erlotinib in TKI-resistant H1975 lung cancer cells …
effect of β-elemene on the antitumor activity of erlotinib in TKI-resistant H1975 lung cancer cells …
Erlotinib-Loaded Poly(ε-Caprolactone) Nanocapsules Improve In Vitro Cytotoxicity and Anticlonogenic Effects on Human A549 Lung Cancer Cells
FA Bruinsmann, JH Buss, GD Souto, E Schultze… - AAPS …, 2020 - Springer
… This study aimed to develop erlotinib (ELB)-loaded poly(ε-caprolactone) nanocapsules (NC
ELB ) and evaluated their in vitro cytotoxicity in A549 cells. The formulation was …
ELB ) and evaluated their in vitro cytotoxicity in A549 cells. The formulation was …
… evaluating emibetuzumab plus erlotinib and emibetuzumab monotherapy in MET immunohistochemistry positive NSCLC patients with acquired resistance to erlotinib
DR Camidge, T Moran, I Demedts, H Grosch… - Clinical lung cancer, 2022 - Elsevier
… in MET diagnostic (+) patients as defined in the current study was not reversed by emibetuzumab
plus erlotinib or emibetuzumab monotherapy. Emibetuzumab was well tolerated, and a …
plus erlotinib or emibetuzumab monotherapy. Emibetuzumab was well tolerated, and a …
[HTML][HTML] β-Elemene enhances erlotinib sensitivity through induction of ferroptosis by upregulating lncRNA H19 in EGFR-mutant non-small cell lung cancer
… Asian non-small cell lung cancer (NSCLC) … research, we found that β-elemene combined
with erlotinib enhanced the cytotoxicity of erlotinib to primary EGFR-TKI-resistant NSCLC cells …
with erlotinib enhanced the cytotoxicity of erlotinib to primary EGFR-TKI-resistant NSCLC cells …
Erlotinib complexation with randomly methylated β-cyclodextrin improves drug solubility, intestinal permeability, and therapeutic efficacy in non-small cell lung cancer
… The purpose of this study was to investigate the impact of anticancer drug erlotinib-randomly …
Phase solubility study showed erlotinib displayed maximum solubility in RAMEB CD …
Phase solubility study showed erlotinib displayed maximum solubility in RAMEB CD …