Articular cartilage degradation and aberrant subchondral bone remodeling in patients with osteoarthritis and osteoporosis

L Chu, X Liu, Z He, X Han, M Yan, X Qu… - Journal of Bone and …, 2020 - academic.oup.com
… in subchondral bone remodeling, … with cartilage degeneration in the hips of patients with
OP‐OA. We hypothesize that aberrant subchondral bone remodeling results in deterioration of …

[HTML][HTML] The difference in joint instability affects the onset of cartilage degeneration or subchondral bone changes

K Arakawa, K Takahata, S Enomoto, Y Oka… - … and Cartilage, 2022 - Elsevier
… articular cartilage degeneration and subchondral bone changesChanges in subchondral
bone were less affected by the … The resorption of subchondral bone was promoted in the ACL-…

Biochemical and morphological abnormalities of subchondral bone and their association with cartilage degeneration in spontaneous osteoarthritis

P Ren, H Niu, H Cen, S Jia, H Gong, Y Fan - Calcified tissue international, 2021 - Springer
… study was to analyze the changes in cartilage composition, subchondral bone structure, and
… to study the treatment and diagnosis of degenerative osteoarthritis. The results in the study …

[HTML][HTML] Bone marrow lesions in knee osteoarthritis: regional differences in tibial subchondral bone microstructure and their association with cartilage degeneration

D Muratovic, DM Findlay, FM Cicuttini, AE Wluka… - … and Cartilage, 2019 - Elsevier
… between subchondral bone microstructure and loss of cartilage integrity and volume. … of
a BML defines the changes in both the subchondral bone and cartilage, which in turn relate to …

Spatial links between subchondral bone architectural features and cartilage degeneration in osteoarthritic joints

S Ajami, B Javaheri, YM Chang, N Maruthainar… - Scientific reports, 2022 - nature.com
… Nevertheless, the significant subchondral bone changes we found including thinner
trabeculae, higher cortical porosity and BS/BV were found in OA patients and not the non-OA …

Subchondral bone microenvironment in osteoarthritis and pain

Y Hu, X Chen, S Wang, Y Jing, J Su - Bone research, 2021 - nature.com
… Furthermore, a significant association between the subchondral bone turnover rate and
cartilage damage has been proven by (99m)Tc-SPECT and 3-T MRI. An elevated number and …

Microstructural analysis of subchondral bone in knee osteoarthritis

LA Holzer, M Kraiger, E Talakic, GA Fritz… - Osteoporosis …, 2020 - Springer
… the degree of cartilage damage varies within the … changes are associated with subchondral
bone changes. In areas of higher cartilage damage, a significantly increased subchondral BV/…

Subchondral bone remodelling in osteoarthritis

S Donell - EFORT open reviews, 2019 - eor.bioscientifica.com
… sclerosis, there is a reduction in the flexibility of the osteochondral junction and a reduction
in the density of the underlying subchondral bone. Articular cartilage degeneration itself …

Type H vessels—a bridge connecting subchondral bone remodelling and articular cartilage degeneration in osteoarthritis development

Y Liu, HQ Xie, B Shen - Rheumatology, 2023 - academic.oup.com
damage to subchondral bone and cartilage degeneration by suppressing type H vessel
formation [55, 56, 75]. However, all these related signalling regulators are still in the basic …

[HTML][HTML] Subchondral bone changes after joint distraction treatment for end stage knee osteoarthritis

SC Mastbergen, A Ooms, TD Turmezei… - … and cartilage, 2022 - Elsevier
changes. The purpose of this research was to explore 3D subchondral bone changes after
cartilage degeneration, but by significant bone remodeling as well 1 . In end-stage knee OA, …