… signaling pathways, potential molecular mechanism, and pathway-associated therapy in
sepsis… Host-derived molecules interacting with activated cells possess pivotal role for sepsis …

… ER stress brings about abnormal apoptosis in sepsis animals, suggesting that ER … pathway
can serve as a novel diagnostic markers and effective therapeutic target for early stage sepsis…

… During the late stage of sepsis, patients can suffer from severe immunosuppression due
to a higher rate of lymphocyte apoptosis and tolerance. Thus, LPS-induced pyroptosis via …

… Recently was been found that pyroptosis is a unique form of proinflammatory programmed
death, that is different from apoptosis. A growing number of studies have investigated …

… manipulating apoptosis could be a new therapeutic approach in sepsis. Further, exploring
potential therapeutic targets related to apoptosis will be valuable in reversing sepsis-induced …

… derived from disassembly of apoptotic cells, now known as apoptotic bodies (ApoBDs). …
of apoptosis were summarized and discussed with a focus on apoptosis-related therapeutic …

… Necroptosis is very common in vivo, in physical traumas, death inflicted by infection and in …
extrinsic apoptotic pathway and therefore emerged as a potential cancer therapeutic target. A …

… Hence, further evaluation of these pathways through experiment and clinical trials may …
pathways of SAE and therapies targeting them. Sepsis-Associated Encephalopathy and Therapy …

… of cell debris arising from apoptosis (80) and necroptosis (81) … sepsis progression markers
than the potential treatment … , this might suggest new therapeutic targets enhancing the …

… Therefore, since MDSCs may be therapeutic target cells for sepsis-induced … CTLA-4
antibody treatment attenuates sepsis-induced apoptosis and improves survival in a …