… Fibroblast activation protein-α (FAP) was first described in … Hence, it was named “fibroblast
activation protein.” In 1990, … important transcription factor for driving FAP expression [34]. …

… of transcriptional activators and suggests that these factors may coordinate transcriptional
activation … models exist to explain the lack of transcription at fertilization: proteins required for …

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …

… They depend on intracellular signaling, which can alter the abundance of AP-1-constituting
proteins via transcriptional regulation of their genes and/or protein stabilization/…

… substrates, including robust NRF2 transcriptional activation (87). Current clinical trials are
testing the efficacy of MLN4924 in patients with hematologic malignancies. Whether NRF2 …

… directly cause transcriptional activation. Additionally, many histone-modifying proteins possess
non-… Given that much remains unknown regarding the functions of these proteins, the field …

… Similarly, WDR5 is a key cofactor for MYCN-regulated transcriptional activation and … region
of target genes to induce transcription of genes involved in protein synthesis and biomass …

… can act as both a transcriptional activator and a repressor. We then … (C/EBP) family proteins
to form heterodimers producing … proteins containing the bZIP domain, including the activating …

… The HIV trans-activator of transcription (Tat) protein was recently shown to recruit the …
Genome-wide studies have expanded our view of CDK9 as a broad transcription activator …

… Enhancers are widely believed to physically contact the target promoters to effect transcriptional
activation. However, our understanding of the full complement of regulatory proteins and …