… Although these reports have been helpful in directing many patients with DOCK8 deficiency
… this article reports on the largest cohort of DOCK8-deficient patients treated by HSCT so far. …

… We conclude that dupilumab is an excellent option for treating DOCK8 deficiency-related
dermatitis in the pediatric population. This observation can also help us learn more about the …

Background DOCK8 deficiency is a primary immunodeficiency in which allogeneic hematopoietic
cell transplantation (HCT) represents the only known cure. We tested the ability of a …

… We suggest that all patients suspected to have DOCK8 deficiency be followed up closely,
and DOCK8 expressions be measured by flow cytometry and confirmed by genetic study and …

… immunodeficiency syndrome (DIDS), sometimes termed DOCK8 deficiency, has been
previously reviewed elsewhere.1-3 DIDS is a combined immunodeficiency that has several …

… HSCT is probably indicated in all patients affected by DOCK8 deficiency. There is considerably
more published HSCT experience for WAS than for DOCK8 deficiency, but many open …

… strategy to efficiently treat DOCK8 deficiency related diseases. But … DOCK8 in immunity and
tumorigenesis, which will help to understand the molecular mechanism of DOCK8 deficiency …

… can greatly improve the clinical condition of some patients. Our results provide insight into
strategies for novel treatments for DOCK8 deficiency, such as gene therapy and adoptive …

… patient with a clinical picture suggestive of DOCK8 deficiency, … 200 DOCK8-deficient patients;
at least 4 other patients have … the suspicion of DOCK8 deficiency and other actinopathies. …

… Here, we report six new mutations causing human DOCK8 deficiency and … in DOCK8-Def.
Therefore, an early diagnosis of DOCK8-Def is essential to facilitate an adequate treatment …