[HTML][HTML] Allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain
C Zhu, X Lan, Z Wei, J Yu, J Zhang - Acta Pharmaceutica Sinica B, 2024 - Elsevier
… Therefore, the development of allosteric modulators targeting the allosteric sites in GPCRs
shows potential in treating neuropathic pain. This review highlights the involvement of several …
shows potential in treating neuropathic pain. This review highlights the involvement of several …
Diagnosis and treatment of painful diabetic peripheral neuropathy
R Pop-Busui, L Ang, AJM Boulton, EL Feldman… - 2022 - Am Diabetes Assoc
… This monograph offers clinicians up-to-date, evidence-based information regarding the
mechanisms involved in inducing nerve fiber damage and neuropathic pain and the spectrum of …
mechanisms involved in inducing nerve fiber damage and neuropathic pain and the spectrum of …
[PDF][PDF] Diabetic neuropathic pain
R Rachmantoko, Z Afif… - … of Pain …, 2021 - download.garuda.kemdikbud.go.id
… , the better understanding of painful diabetic neuropathic underlying mechanism can help
to find a better management that improving the guideline quality in optimalizing pain control. …
to find a better management that improving the guideline quality in optimalizing pain control. …
[HTML][HTML] Pregabalin and gabapentin in neuropathic pain management after spinal cord injury: a systematic review and meta-analysis
… The findings of this study suggest that both PGB and GBP are effective in the treatment of
neuropathic pain associated with SCI. Likewise, head-to-head studies showed that there was …
neuropathic pain associated with SCI. Likewise, head-to-head studies showed that there was …
Translational issues in precision medicine in neuropathic pain
AH Dickenson, R Patel - Canadian Journal of Pain, 2020 - Taylor & Francis
… Neuropathic pain remains poorly treated, with most new drugs falling through the translational
gap. The traditional model of bench-to-bedside research has relied on identifying new …
gap. The traditional model of bench-to-bedside research has relied on identifying new …
[HTML][HTML] In vitro and in vivo effects of flavonoids on peripheral neuropathic pain
P Basu, A Basu - Molecules, 2020 - mdpi.com
… for treating neuropathic pain conditions. Flavonoids have been reported to alleviate neuropathic
pain … flavonoids attenuate different peripheral neuropathic pain conditions at behavioral, …
pain … flavonoids attenuate different peripheral neuropathic pain conditions at behavioral, …
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain
J Li, M Tian, T Hua, H Wang, M Yang, W Li, X Zhang… - Autophagy, 2021 - Taylor & Francis
… Our studies showed that activation of autophagy could relieve pain during both neuropathic
pain … needs to be studied to further regulate autophagy and treat neuropathic pain more …
pain … needs to be studied to further regulate autophagy and treat neuropathic pain more …
Potential biomarkers for persistent and neuropathic pain therapy
M Sisignano, J Lötsch, MJ Parnham… - Pharmacology & …, 2019 - Elsevier
… of treatment of neuropathic pain in patients. Similarly, patients with FEPS1 will probably
benefit from an individualized therapy with one of the many novel TRPA1 antagonists under …
benefit from an individualized therapy with one of the many novel TRPA1 antagonists under …
[HTML][HTML] Facilitation of MrgprD by TRP-A1 promotes neuropathic pain
… of neuropathic pain. Our findings reveal a novel mechanism of neuropathic pain formation
and highlight MrgprD as a promising drug target for the treatment of neuropathic pain.—Wang, …
and highlight MrgprD as a promising drug target for the treatment of neuropathic pain.—Wang, …
Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary: report of the AAN guideline subcommittee
R Price, D Smith, G Franklin, G Gronseth, M Pignone… - Neurology, 2022 - AAN Enterprises
… A treatment to reduce neuropathic pain in a patient should … outweigh any benefit in reduced
neuropathic pain. While the exact side … An intervention to relieve neuropathic pain should be …
neuropathic pain. While the exact side … An intervention to relieve neuropathic pain should be …