Insights into the role of sialylation in cancer progression and metastasis

C Dobie, D Skropeta - British Journal of Cancer, 2021 - nature.com
… This can be achieved by mimicking the glycosylation patterns of healthy immune cells …
cancer stemness. While they could be expected to work in concert to promote tumour progression, …

Aberrant protein glycosylation in cancer: implications in targeted therapy

JG Rodrigues, HO Duarte, CA Reis… - Biochemical Society …, 2021 - portlandpress.com
… In this sense, aberrant in vivo patterns of tumour cell glycosylation may represent a hindrance
underlying limited clinical activity of pre-clinically validated mAbs, by masking or hiding …

Altered glycosylation in cancer: A promising target for biomarkers and therapeutics

D Thomas, AK Rathinavel, P Radhakrishnan - … (BBA)-Reviews on Cancer, 2021 - Elsevier
… We discuss how altered glycosylation machinery is associated with cancer progression and
… influence of aberrant glycosylation in the development of cancer biomarkers and targeted …

Protein glycosylation and tumor microenvironment alterations driving cancer hallmarks

A Peixoto, M Relvas-Santos, R Azevedo… - Frontiers in …, 2019 - frontiersin.org
… of cancer (39). As such, we reinforce this notion by highlighting aberrant glycosylation as an
integral part of all recognized cancer … features for tumor progression and aggressiveness. …

The glycosylation landscape of pancreatic cancer

J Munkley - Oncology Letters, 2019 - spandidos-publications.com
… crucial roles for glycans during all steps of tumour progression. Glycans can regulate … in
glycosylation involved in pancreatic cancer, their role in disease development and progression, …

Glycosylation and metastases

D Josic, T Martinovic, K Pavelic - Electrophoresis, 2019 - Wiley Online Library
glycosylation is one of the key events in malignant transformation and neoplastic progression,
and tumor-related glycosylation … Both malignant transformation and neoplastic progression

Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis

H Läubli, L Borsig - Frontiers in immunology, 2019 - frontiersin.org
Cancer-associated glycosylation promotes the interaction of tumor cells within a … the context
of altered glycosylation as a ubiquitous characteristic of cancer progression with a focus on …

The role of glycosylation in melanoma progression

C De Vellis, S Pietrobono, B Stecca - Cells, 2021 - mdpi.com
… how these events of aberrant glycosylation play a role in melanoma progression. … in
glycosylation involved in melanoma progression and provided inputs to exploit aberrant glycosylation

Glycosylation markers in cancer

A Silsirivanit - Advances in clinical chemistry, 2019 - Elsevier
cancer would likely facilitate diagnosis and treatment. In this chapter, the alteration of protein
glycosylation … de Llorens, Altered glycosylation in tumours focused to cancer diagnosis, Dis. …

Targeting glycosylation: a new road for cancer drug discovery

AF Costa, D Campos, CA Reis, C Gomes - Trends in cancer, 2020 - cell.com
… targeting has the potential to start a new era of cancer therapy. In this article, we discuss
the promise of cancer-associated glycosylation for the discovery of effective cancer drugs. …