Current status of photodynamic technology for urothelial cancer

K Inoue, H Fukuhara, S Yamamoto… - Cancer …, 2022 - Wiley Online Library
… the mitochondria of tumor cells emits red fluorescent light in the range of 600-740 nm. By
using 5-ALA as a photosensitizer to produce red fluorescence in tumor cells, tumor cells can be …

The cancer immunogram as a framework for personalized immunotherapy in urothelial cancer

N van Dijk, SA Funt, CU Blank, T Powles… - European urology, 2019 - Elsevier
… Other amino acids essential for T-cell and tumor cell metabolism and function are
arginine and glutamine. Preclinical data demonstrated that arginine depletion inhibits T-…

Circulating tumor cell and circulating tumor DNA assays reveal complementary information for patients with metastatic urothelial cancer

HJ Chalfin, SA Glavaris, MA Gorin, MR Kates… - European urology …, 2021 - Elsevier
… New “liquid biopsy” blood tests are emerging for urothelial cancer aimed at … tumor cells
may be best for studying the biological features of a person’s cancer, whereas circulating tumor

Prognostic and predictive value of tumor-infiltrating immune cells in urothelial cancer of the bladder

S van Wilpe, ECF Gerretsen, AG van der Heijden… - Cancers, 2020 - mdpi.com
… and selectively eradicate cancer cells. During progression to clinically manifest cancer,
tumor cells acquire mechanisms to escape immune surveillance. Tumors may lose antigenicity …

Urothelial carcinoma of the bladder induces endothelial cell activation and hypercoagulation

A John, JR Robador, S Vidal-y-Sy, P Houdek… - Molecular Cancer …, 2020 - AACR
… and reduced survival in patients with urothelial cancer of the bladder. Although previous …
tumor cell–derived VEGF-A and endothelial VWF as procoagulant mediators in bladder cancer

Mouse and human urothelial cancer organoids: A tool for bladder cancer research

J Mullenders, E de Jongh, A Brousali… - Proceedings of the …, 2019 - National Acad Sciences
… bladder cancer cells and mouse primary urothelial cells. This culture method is based on
the previously established organoid cultures for human and mouse normal and tumor cells (23, …

Evaluation of HER2 expression in urothelial carcinoma cells as a biomarker for circulating tumor cells

A Nini, MJ Hoffmann, R Lampignano… - Cytometry Part B …, 2020 - Wiley Online Library
… in the present study may be linked to EMT of the tumor cells, with reduced expression of
EpCAM. Furthermore, EpCAM expression on the cell surface may be limited by shedding. Thus, …

Molecular pathology of urothelial carcinoma

A Lopez-Beltran, A Cimadamore, R Montironi, L Cheng - Human pathology, 2021 - Elsevier
… of urothelial cancer may require experimental design to address tumor heterogeneity–related …
of tumor cells and their microenvironments (immune cells, fibroblasts, and smooth muscle …

The antitumor effect of curcumin in urothelial cancer cells is enhanced by light exposure in vitro

F Roos, K Binder, J Rutz, S Maxeiner… - Evidence‐Based …, 2019 - Wiley Online Library
… Though curcumin alone did not alter cell proliferation or apoptosis, tumor cell growth and …
Curcumin-light caused the bladder cancer cells to become arrested in different cell phases: G0/…

Enfortumab Vedotin in urothelial cancer

M Alt, C Stecca, S Tobin, DM Jiang… - … advances in urology, 2020 - journals.sagepub.com
… of the tumor cell. Ideally the antigen should be expressed at higher levels in tumor tissue …
This preferentially increases the uptake into tumor cells compared with normal cells, and …