[HTML][HTML] A new role for old friends: effects of helminth infections on vaccine efficacy

F Zhu, W Liu, T Liu, L Shi, W Zheng, F Guan, J Lei - Pathogens, 2022 - mdpi.com
… mechanism by which helminths affect vaccine effectiveness. … of helminth infections and
their treatment on vaccination in … influence of helminth infections on SARS-CoV-2 vaccine was …

[HTML][HTML] Helminth infections suppress the efficacy of vaccination against seasonal influenza

W Hartmann, ML Brunn, N Stetter, N Gagliani… - Cell reports, 2019 - cell.com
helminth infections on the efficacy of vaccinations using Litomosoides sigmodontis-infected
Here, we compare the efficacy of vaccinations against seasonal influenza that were licensed …

The effect of helminth infection on vaccine responses in humans and animal models: A systematic review and meta‐analysis

A Natukunda, L Zirimenya, J Nassuuna… - Parasite …, 2022 - Wiley Online Library
… coverage is on the rise including in low- and middle-income countries, efficacy and
immunogenicity of some vaccines varies greatly by population and geographic location, with …

[HTML][HTML] Soil-transmitted helminth vaccines: are we getting closer?

A Zawawi, KJ Else - Frontiers in immunology, 2020 - frontiersin.org
… , helminth infections are spreading into new areas. Thus, there is a strong rationale for
developing anthelminthic vaccines … safety, immunogenicity, and efficacy of vaccines; and some of …

[HTML][HTML] Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

O Nouatin, JB Mengue, JC Dejon-Agobé… - PLoS neglected …, 2021 - journals.plos.org
… of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria vaccine
candidate, … Controlled human malaria infection (CHMI) was used to assess the efficacy of the …

Intestinal helminth infection impairs oral and parenteral vaccine efficacy

Y Zhang, LKC Hardy, CM Kapita, JA Hall… - The Journal of …, 2023 - journals.aai.org
… Ten days after helminth infection and 3 d after oral vaccination, we found comparable … -TCR
Tg Th1 cells in the draining MLNs among helminth-infected and helminth-free mice (Fig. 6B, …

The yin and yang of human soil-transmitted helminth infections

A Loukas, RM Maizels, PJ Hotez - International journal for parasitology, 2021 - Elsevier
… Despite high efficacy, animals showed residual levels of infection that dented confidence
in … The absence of vaccines for any human helminth infection can be attributed to a lack of …

[HTML][HTML] Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice

W Hartmann, ML Brunn, N Stetter, G Gabriel, M Breloer - Plos one, 2022 - journals.plos.org
infection of vaccination efficacy should be addressed [13, 14]… with vaccination efficacy by
underlying helminth infections in … -infected mice as a model for chronic human filarial infections […

[HTML][HTML] Promising technologies in the field of helminth vaccines

DJ Perera, M Ndao - Frontiers in immunology, 2021 - frontiersin.org
… will summarize various helminth vaccination techniques and compare their efficacy for …
no RNA vaccines developed against helminthic infections, however DNA vaccines have been …

[HTML][HTML] A combination of deworming and prime-boost vaccination regimen restores efficacy of vaccination against influenza in helminth-infected mice

N Stetter, W Hartmann, ML Brunn… - Frontiers in …, 2021 - frontiersin.org
… of helminth-infected individuals to vaccinations may be impaired as well. Here we study the
impact of helminth-induced immunomodulation on vaccination efficacy … sigmodontis infection