Regulation of ZEB1 function and molecular associations in tumor progression and metastasis
M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
… of ZEB1 in mediating tumor progression and metastasis and describe the ways in which protein
modifications can regulate its molecular associations and function… regulation of ZEB1′s …
modifications can regulate its molecular associations and function… regulation of ZEB1′s …
[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications
Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
… ZEB1 … ZEB1 and these chromatin-modifying enzymes may represent an efficient for treating
cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic progression …
cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic progression …
ZEB1: New advances in fibrosis and cancer
L Cheng, MY Zhou, YJ Gu, L Chen, Y Wang - Molecular and Cellular …, 2021 - Springer
… structure of ZEB1 and the protein binding sites of ZEB1 with some … roles of ZEB1 in fibrosis
and cancer progression to elaborate … , ZEB1 facilitates tumor progression and promotes tumor …
and cancer progression to elaborate … , ZEB1 facilitates tumor progression and promotes tumor …
Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies
R Fu, Y Li, N Jiang, BX Ren, CZ Zang… - The Journal of …, 2020 - Am Soc Clin Investig
… of vascular ZEB1 in tumor progression, we evaluated LLC and B16F10 tumor models by
subcutaneous implantation of LLC and B16F10 cells into 9-week-old Zeb1 WT and Zeb1 iΔEC …
subcutaneous implantation of LLC and B16F10 cells into 9-week-old Zeb1 WT and Zeb1 iΔEC …
[HTML][HTML] ZEB1: catalyst of immune escape during tumor metastasis
J Lu, F Fei, C Wu, J Mei, J Xu, P Lu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
… in ZEB1 expression and its role in tumor immune evasion, which may make it a promising
therapeutic target for tumor … tumor progression by regulating miR-139–5p expression [48]. …
therapeutic target for tumor … tumor progression by regulating miR-139–5p expression [48]. …
Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer
HT Wu, HT Zhong, GW Li, JX Shen, QQ Ye… - Journal of translational …, 2020 - Springer
… Therefore, further investigations to reveal the contribution of various tumor
microenvironmental factors to tumor progression will lead to a comprehensive understanding of …
microenvironmental factors to tumor progression will lead to a comprehensive understanding of …
Prognostic value of ZEB-1 in solid tumors: a meta-analysis
B Chen, B Chen, Z Zhu, W Ye, J Zeng, G Liu, S Wang… - BMC cancer, 2019 - Springer
… The inclusion criteria were as follows: (1) diagnosis of human solid tumor; (2) the role of
ZEB-1 in the tumor progression must be investigated; (3) description of the relevance of …
ZEB-1 in the tumor progression must be investigated; (3) description of the relevance of …
Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells
Y Guo, X Lu, Y Chen, B Rendon, RA Mitchell… - Science …, 2021 - science.org
… Zeb1-AD cells, Zeb1 lo AC cells in the central tumor in TGFb1-deficient regions, and clusters
of Zeb1 hi invading AC cells at the tumor … Zeb1, PDL1, and CD47 during tumor progression; …
of Zeb1 hi invading AC cells at the tumor … Zeb1, PDL1, and CD47 during tumor progression; …
Loss of circadian gene Timeless induces EMT and tumor progression in colorectal cancer via Zeb1-dependent mechanism
T Colangelo, A Carbone, F Mazzarelli… - Cell Death & …, 2022 - nature.com
… low-TIM/high-ZEB1 expression have a poorer outcome. … -ZEB1 axis in key pathological
processes driving malignant phenotype acquisition in colorectal carcinogenesis. Thus, TIM-ZEB1 …
processes driving malignant phenotype acquisition in colorectal carcinogenesis. Thus, TIM-ZEB1 …
ISL1 predicts poor outcomes for patients with gastric cancer and drives tumor progression through binding to the ZEB1 promoter together with SETD7
T Guo, XZ Wen, Z Li, H Han, C Zhang, Y Bai… - Cell death & …, 2019 - nature.com
… ZEB1, a key regulator of the epithelial–mesenchymal transition (EMT). Meanwhile, we validated
ISL1 as activating ZEB1 … can directly bind to the ZEB1 promoter to activate its expression …
ISL1 as activating ZEB1 … can directly bind to the ZEB1 promoter to activate its expression …
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