Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer

JN Diehl, PS Hibshman, I Ozkan-Dagliyan… - Advances in Cancer …, 2022 - Elsevier
Mutational activation of the KRAS oncogene is found in~ 95% of pancreatic ductal
adenocarcinoma (PDAC), the major form of pancreatic cancer. With substantial experimental …

Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer.

JN Diehl, PS Hibshman, I Ozkan-Dagliyan… - Advances in Cancer …, 2021 - europepmc.org
Mutational activation of the KRAS oncogene is found in~ 95% of pancreatic ductal
adenocarcinoma (PDAC), the major form of pancreatic cancer. With substantial experimental …

Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer

JN Diehla, PS Hibshmanb… - RAS: Past, Present …, 2022 - books.google.com
7. Inhibition of the RAF-MEK-ERK cascade: Promises and challenges 8. ERK regulation of a
diverse phosphoproteome and transcriptome 9. MYC: The critical determinant for ERK …

Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer

JN Diehl, PS Hibshman… - … in cancer research, 2022 - pubmed.ncbi.nlm.nih.gov
Mutational activation of the KRAS oncogene is found in~ 95% of pancreatic ductal
adenocarcinoma (PDAC), the major form of pancreatic cancer. With substantial experimental …