Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo

VL Alvarez, Y Tao, Y Li, W Du, M Whittaker, J Zuris… - 2022 - researchsquare.com
Mutations in Atp2b2, an outer hair cell (OHC) gene, cause dominant hearing loss (HL) in
humans. Using a mouse model Atp2b2Obl+, with a dominant HL mutation (Oblivion), we …

[PDF][PDF] ribonucleoprotein delivery in vivo

VL Alvarez, Y Tao, Y Li, W Du, M Whittaker, J Zuris… - scholar.archive.org
Mutations in Atp2b2, an outer hair cell (OHC) gene, cause dominant hearing loss (HL) in
humans. Using a mouse model Atp2b2Obl+, with a dominant HL mutation (Oblivion), we …

Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo

VL Alvarez, Y Tao, Y Li, W Du, M Whittaker, J Zuris… - 2022 - europepmc.org
Mutations in Atp2b2, an outer hair cell (OHC) gene, cause dominant hearing loss (HL) in
humans. Using a mouse model Atp2b2Obl+, with a dominant HL mutation (Oblivion), we …

[PDF][PDF] ribonucleoprotein delivery in vivo

VL Alvarez, Y Tao, Y Li, W Du, M Whittaker, J Zuris… - assets-eu.researchsquare.com
Mutations in Atp2b2, an outer hair cell (OHC) gene, cause dominant hearing loss (HL) in
humans. Using a mouse model Atp2b2Obl+, with a dominant HL mutation (Oblivion), we …