Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4–LEF1 Binding

CB Lanauze, P Sehgal, K Hayer, M Torres-Diz… - Molecular Cancer …, 2021 - AACR
Abstract About 10% to 30% of patients with colorectal cancer harbor either loss of or
missense mutations in SMAD4, a critical component of the TGFβ signaling pathway. The …
被引用次数：3 相关文章

Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4-LEF1 Binding.

CB Lanauze, P Sehgal, K Hayer… - Molecular Cancer …, 2021 - europepmc.org
30% of colorectal cancer (CRC) patients harbor either loss of or missense mutations in
SMAD4, a critical component of the TGFβ signaling pathway. The pathophysiological …

Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4-LEF1 Binding

CB Lanauze, P Sehgal, K Hayer… - Molecular cancer …, 2021 - pubmed.ncbi.nlm.nih.gov
About 10% to 30% of patients with colorectal cancer harbor either loss of or missense
mutations in SMAD4, a critical component of the TGFβ signaling pathway. The …
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[HTML][HTML] Colorectal cancer-associated Smad4 R361 hotspot mutations boost Wnt/β-catenin signaling through enhanced Smad4-LEF1 binding

CB Lanauze, P Sehgal, K Hayer… - Molecular cancer …, 2021 - ncbi.nlm.nih.gov
30% of colorectal cancer (CRC) patients harbor either loss of or missense mutations in
SMAD4, a critical component of the TGFβ signaling pathway. The pathophysiological …

Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4-LEF1 Binding.

CB Lanauze, P Sehgal, K Hayer… - Molecular Cancer …, 2021 - europepmc.org
30% of colorectal cancer (CRC) patients harbor either loss of or missense mutations in
SMAD4, a critical component of the TGFβ signaling pathway. The pathophysiological …