[HTML][HTML] Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies

Z Liu, K Gunasekaran, W Wang, V Razinkov… - Journal of Biological …, 2014 - ASBMB
Antibody-dependent cellular cytotoxicity (ADCC) is mediated through the engagement of the
Fc segment of antibodies with Fcγ receptors (FcγRs) on immune cells upon binding of tumor …

Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.

Z Liu, K Gunasekaran, W Wang, V Razinkov… - The Journal of …, 2013 - europepmc.org
Antibody-dependent cellular cytotoxicity (ADCC) is mediated through the engagement of the
Fc segment of antibodies with Fcγ receptors (FcγRs) on immune cells upon binding of tumor …

Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies

Z Liu, K Gunasekaran, W Wang… - The Journal of …, 2014 - pubmed.ncbi.nlm.nih.gov
Antibody-dependent cellular cytotoxicity (ADCC) is mediated through the engagement of the
Fc segment of antibodies with Fcγ receptors (FcγRs) on immune cells upon binding of tumor …

[PDF][PDF] AsymmetricalFcEngineeringGreatlyEnhancesAntibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies

Z Liu, K Gunasekaran, W Wang… - THE JOURNAL OF …, 2014 - researchgate.net
Background: Co-crystal structure of Fc-Fc RIII complex revealed that Fc binds to Fc RIII
asymmetrically. Results: We identified a panel of novel Fc heterodimers with enhanced …

[HTML][HTML] Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies

Z Liu, K Gunasekaran, W Wang… - The Journal of …, 2014 - ncbi.nlm.nih.gov
Background: Co-crystal structure of Fc-FcγRIII complex revealed that Fc binds to FcγRIII
asymmetrically. Results: We identified a panel of novel Fc heterodimers with enhanced …

[HTML][HTML] Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies

Z Liu, K Gunasekaran, W Wang, V Razinkov… - Journal of Biological …, 2014 - Elsevier
Antibody-dependent cellular cytotoxicity (ADCC) is mediated through the engagement of the
Fc segment of antibodies with Fcγ receptors (FcγRs) on immune cells upon binding of tumor …

[引用][C] Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies

Z Liu, K Gunasekaran, W Wang, V Razinkov… - Journal of Biological …, 2014 - cir.nii.ac.jp
Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC)
Effector Function and Stability of the Modified Antibodies | CiNii Research CiNii 国立情報学 …

Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.

Z Liu, K Gunasekaran, W Wang, V Razinkov… - The Journal of …, 2013 - europepmc.org
Antibody-dependent cellular cytotoxicity (ADCC) is mediated through the engagement of the
Fc segment of antibodies with Fcγ receptors (FcγRs) on immune cells upon binding of tumor …