Targeting liver angiotensinogen using a GalNAc-siRNA improves cardiac remodeling in spontaneously hypertensive rats

J Johannes Wikstrom, J Liang, H Cao… - European Heart …, 2023 - academic.oup.com
Abstract Background Dysregulation of the Renin-Angiotensin-Aldosterone System (RAAS)
leads to hypertension and cardiac hypertrophy. Angiotensinogen (AGT) is the only precursor …
相关文章

Targeting liver angiotensinogen using a GalNAc-siRNA improves cardiac remodeling in spontaneously hypertensive rats

J Johannes Wikstrom, J Liang, H Cao… - European Heart …, 2023 - academic.oup.com
Abstract Background Dysregulation of the Renin-Angiotensin-Aldosterone System (RAAS)
leads to hypertension and cardiac hypertrophy. Angiotensinogen (AGT) is the only precursor …