The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2017 - Elsevier
Highlights•Dose selection for new combination therapy in tuberculosis has remained
empirical.•Novel tools are needed for effective translation of preclinical models to humans.•A …

The implications of model-informed drug discovery and development for tuberculosis.

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2016 - europepmc.org
Despite promising advances in the field and highly efficacious first-line treatment, an
estimated 9.6 million people are still infected with tuberculosis (TB). Innovative methods are …

[PDF][PDF] The implications of model–informed drug discovery and development for tuberculosis

MMGRD Ulrika, SHSSHG Oscar, D Pasqua… - 2016 - core.ac.uk
Despite promising advances in the field and highly effective first-line treatment, an estimated
9.6 million people are still infected with tuberculosis (TB). Innovative methods are required to …

The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2017 - diva-portal.org
Despite promising advances in the field and highly efficacious first-line treatment, an
estimated 9.6 million people are still infected with tuberculosis (TB). Innovative methods are …

The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2016 - discovery.ucl.ac.uk
Despite promising advances in the field and highly effective first-line treatment, an estimated
9.6 million people are still infected with tuberculosis (TB). Innovative methods are required to …

The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies… - Drug discovery …, 2017 - pubmed.ncbi.nlm.nih.gov
Despite promising advances in the field and highly efficacious first-line treatment, an
estimated 9.6 million people are still infected with tuberculosis (TB). Innovative methods are …

The implications of model–informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies… - Drug …, 2017 - research-portal.st-andrews.ac.uk
Despite promising advances in the field and highly effective first-line treatment, an estimated
9.6 million people are still infected with tuberculosis (TB). Innovative methods are required to …

The implications of model–informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies… - Drug …, 2017 - research-repository.st-andrews.ac …
Despite promising advances in the field and highly effective first-line treatment, an estimated
9.6 million people are still infected with tuberculosis (TB). Innovative methods are required to …

The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2017 - infona.pl
Despite promising advances in the field and highly efficacious first-line treatment, an
estimated 9.6 million people are still infected with tuberculosis (TB). Innovative methods are …

The implications of model-informed drug discovery and development for tuberculosis

M Muliaditan, GR Davies, USH Simonsson… - Drug Discovery …, 2017 - infona.pl
Despite promising advances in the field and highly efficacious first-line treatment, an
estimated 9.6 million people are still infected with tuberculosis (TB). Innovative methods are …