A guide to plasma membrane solute carrier proteins
MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
… an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and
their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 …
their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 …
[HTML][HTML] An overview of cell-based assay platforms for the solute carrier family of transporters
V Dvorak, T Wiedmer, A Ingles-Prieto… - Frontiers in …, 2021 - frontiersin.org
… For each SLC, the localization at the plasma membrane, the electrogenicity and the main
substrate class are annotated. Annotation information regarding localization and substrate was …
substrate class are annotated. Annotation information regarding localization and substrate was …
[HTML][HTML] Systematic in silico discovery of novel solute carrier-like proteins from proteomes
G Gyimesi, MA Hediger - PLoS One, 2022 - journals.plos.org
… In this regard, we believe that our work provides correlation between transporter proteins in
… , it is localized to both the plasma membrane and intracellular membrane compartments [64]. …
… , it is localized to both the plasma membrane and intracellular membrane compartments [64]. …
[HTML][HTML] A structure and evolutionary-based classification of solute carriers
E Ferrada, G Superti-Furga - Iscience, 2022 - cell.com
… gene member of the nucleoside-sugar transport family … cell membrane at rates required
by cellular physiology, organisms have evolved membrane proteins that facilitate the transport …
by cellular physiology, organisms have evolved membrane proteins that facilitate the transport …
New and emerging research on solute carrier and ATP binding cassette transporters in drug discovery and development: outlook from the international transporter …
… on the plasma membrane. … of transporter protein expression levels in key ADME-related
organs, such as the intestines, liver, and kidneys followed by a short description of transporter …
organs, such as the intestines, liver, and kidneys followed by a short description of transporter …
Emerging roles of the human solute carrier 22 family
SW Yee, KM Giacomini - Drug Metabolism and Disposition, 2022 - ASPET
… organic ion transporter family, consists of 28 distinct multi-membrane spanning proteins, which
… that function to move substrates across the plasma membrane by one of the mechanisms (…
… that function to move substrates across the plasma membrane by one of the mechanisms (…
[HTML][HTML] Substrate specificities and inhibition pattern of the solute carrier family 10 members NTCP, ASBT and SOAT
G Grosser, SF Müller, M Kirstgen, B Döring… - Frontiers in molecular …, 2021 - frontiersin.org
… Three carriers of the solute carrier family SLC10 have been functionally characterized so
far. Na + /taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and …
far. Na + /taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and …
Solute carrier transporters as potential targets for the treatment of metabolic disease
T Schumann, J König, C Henke, DM Willmes… - Pharmacological …, 2020 - ASPET
The solute carrier (SLC) superfamily comprises more than 400 transport proteins mediating …
ions, nucleotides, and sugars across biological membranes. Over 80 SLC transporters have …
ions, nucleotides, and sugars across biological membranes. Over 80 SLC transporters have …
The concise guide to pharmacology 2021/22: Transporters
SPH Alexander, E Kelly, A Mathie… - British Journal of …, 2021 - Wiley Online Library
… Within the solute carrier family, there are a great variety of solutes transported, from simple
… plasma membrane, or solute transport into and out of cellular organelles. Some SLC family …
… plasma membrane, or solute transport into and out of cellular organelles. Some SLC family …
A substrate‐based ontology for human solute carriers
E Meixner, U Goldmann, V Sedlyarov… - Molecular Systems …, 2020 - embopress.org
… membranes, as well as the plasma membrane. We found that nearly two-thirds of annotated
SLCs have been reported to be localized, at least partially, on the plasma membrane. The …
SLCs have been reported to be localized, at least partially, on the plasma membrane. The …