… of metabolic health, in the present study we sought to determine whether dietary carbohydrates
modulate energetic, metabolic, and islet adaptions to high-saturated fat diets in male and …

… While glucose and AA are supplied from dietary carbohydrates … metabolism are markedly
modulated by other fuels (eg, … and/or hypercholesterolemia (high-fat diet–fed mice, ZDF rats, …

… Previously, we and others reported that chronic consumption of high-carbohydrates or high-fat
content diets induce a cytotoxic state related with overweight or obesity, characterized by …

… There were increases in the insulin-positive area, β cell mass and β cell proliferation in …
affect β cell apoptosis in mouse offspring and found that there was no significant change in β cell …

… PKC and modulating insulin granule exocytosis [31,32]. … β-cell mass induced by recurrent
hyperglycemia is β-cell … were reduced in high-fat diet-induced obese mice exhibiting early and …

… in altering the carbohydrates and lipids metabolism. Similarly, … transcriptional activity of key
β-cell genes thus creating insulin … miR-184 modulates cardiomyocyte insulin sensitivity by …

… -decompensation adaptation of β cell function in response to increasing duration of high-fat …
on CTCF binding sites may directly modulate the transcriptional activation of corresponding …

… diet induced M2-type macrophage polarization, as well as cytokine production modulation by
the low-carbohydrate … use of low-carb, high-fat (LCHF) diets for obesity treatment, this study …

… In this study, we characterized the metabolic phenotypes of … compensatory increases in β-cell
mass and hyperinsulinemia. … were more susceptible to diet-induced obesity. We measured …

… mice adapted better to a HFD despite their altered metabolic … Next, to test if CAV1 modulates
MAPK activation in beta cells … with insulin resistance and diet-induced obesity in rats [48] …