GlgA plays an important role in the induction of hydrosalpinx by Chlamydia muridarum
C Hu, H Wu, Y Sun, J Kong, LL Shao… - Pathogens and …, 2020 - academic.oup.com
… of GlgA deficiency on hydrosalpinx induction in mice. We selected two C. muridarum strains
with GlgA … muridarum. The two mutant isolates had different site mutations that would lead to …
with GlgA … muridarum. The two mutant isolates had different site mutations that would lead to …
Tryptophan residue of plasmid-encoded Pgp3 is important for Chlamydia muridarum to induce hydrosalpinx in mice
Y Huang, H Wu, Y Sun, Y Liu - Frontiers in Microbiology, 2023 - frontiersin.org
… Pgp3 and GlgA protein expression … GlgA expression (Figure 2). However, although Pgp3
immunoactivity was detected in cultures infected with Pgp3Y197A or Pgp3W234A C. muridarum…
immunoactivity was detected in cultures infected with Pgp3Y197A or Pgp3W234A C. muridarum…
A chlamydial plasmid-dependent secretion system for the delivery of virulence factors to the host cytosol
L Lei, C Yang, MJ Patton, M Smelkinson, D Dorward… - Mbio, 2021 - Am Soc Microbiol
… role of GlgA in chlamydial pathogenesis remains poorly defined, nonisogenic Chlamydia
muridarum strains with GlgA … Expression of GlgA/His fusion protein was induced with isopropyl-…
muridarum strains with GlgA … Expression of GlgA/His fusion protein was induced with isopropyl-…
Identification of HeLa cell proteins that interact with Chlamydia trachomatis glycogen synthase using yeast two‑hybrid assays
Z Sun, Y Sun, Y Li, X Luan, H Chen… - Molecular …, 2020 - spandidos-publications.com
… genital tract can result in tubal fibrosis and hydrosalpinx. Therefore, the aim of the present
… whether GlgA secretion into the host cell cytosol is necessary for the induction of chlamydial …
… whether GlgA secretion into the host cell cytosol is necessary for the induction of chlamydial …
Co-ordinated regulation of pathways controlling chlamydial virulence and stress response
SY Omesi - 2021 - cdr.lib.unc.edu
… served a regulatory role in the expression of pgp3 and glgA, … deficient strain of C.muridarum
was associated with a highly … is associated with failure to induce hydrosalpinx, a condition …
was associated with a highly … is associated with failure to induce hydrosalpinx, a condition …
Chlamydia trachomatis glycogen synthase promotes MAPK-mediated proinflammatory cytokine production via TLR2/TLR4 in THP-1 cells
Z Sun, Y Li, H Chen, L Xie, J Xiao, X Luan, B Peng, Z Li… - Life sciences, 2021 - Elsevier
… chlamydial component GlgA is secreted into host cells, we sought to determine whether GlgA
is capable of inducing … A recent study showed that GlgA deficiency reduced hydrosalpinx …
is capable of inducing … A recent study showed that GlgA deficiency reduced hydrosalpinx …
[HTML][HTML] Plasmid-mediated virulence in Chlamydia
BJ Turman, T Darville, CM O'Connell - Frontiers in Cellular and …, 2023 - ncbi.nlm.nih.gov
… to immune responses induced by chlamydial infection at these … The absence of Pgp4
and consequent reduced glgA … muridarum developed hydrosalpinx compared to 80% for …
and consequent reduced glgA … muridarum developed hydrosalpinx compared to 80% for …
Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation
B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
… muridarum vaginal infection induces hydrosalpinx in mice, similar to female fallopian tube …
in chlamydial pathogenesis since Pgp3-deficient C. muridarum failed to induce hydrosalpinx …
in chlamydial pathogenesis since Pgp3-deficient C. muridarum failed to induce hydrosalpinx …
Chlamydia trachomatis plasmid gene protein 3 is essential for the establishment of persistent infection and associated immunopathology
… chromosomal genes, including GlgA, CT049-CT050, … significant reduction in shedding
duration in the ocular trachoma model (17), leading to the hypothesis that the plasmid plays a role …
duration in the ocular trachoma model (17), leading to the hypothesis that the plasmid plays a role …
Can't live outside you: a thematic issue on obligate intracellular bacterial pathogens
… ubiquitous swine pathogen Chlamydia suis provide insights into evolutionary dynamics of
the Chlamydia genus and identify gene sets specific to certain Chlamydia species as potential …
the Chlamydia genus and identify gene sets specific to certain Chlamydia species as potential …