Mouse models of sarcopenia: classification and evaluation

W Xie, M He, D Yu, Y Wu, X Wang, S Lv… - … , sarcopenia and …, 2021 - Wiley Online Library
animal models is particularly important. In this paper, we will review the different mouse models
of sarcopenia, … the pathophysiology of sarcopenia, and evaluate the different therapeutic …

[HTML][HTML] Two types of mouse models for sarcopenia research: senescence acceleration and genetic modification models

KW Baek, YK Jung, JS Park, JS Kim… - Journal of Bone …, 2021 - ncbi.nlm.nih.gov
mouse models in research may be relatively narrow, but there are mouse models that can
be reasonably used in sarcopenia … this review, we introduce accelerated senescence mouse

[HTML][HTML] Rodent model of muscular atrophy for sarcopenia study

KW Baek, YK Jung, JS Kim, JS Park… - Journal of bone …, 2020 - ncbi.nlm.nih.gov
… Therefore, when judged comprehensively, selecting an animal with an extreme-value after
evaluating skeletal muscle mass and grip strength, etc. in aging rodents is probably the most …

Complementary combination of biomarkers for diagnosis of sarcopenia in C57BL/6J mice

N Van Long, PN Chien, TX Tung, NN Giang, PT Nga… - Life Sciences, 2023 - Elsevier
… natural aging model, which may not reflect correctly sarcopenic … an evaluation of multiple
biomarkers for sarcopenia from … in a naturally aging mouse model. The digital biomarkers relate …

The potential of traditional herbal active ingredients in the treatment of sarcopenia animal models: focus on therapeutic effects and mechanisms

K Ding, W Jiang, J Zhangwang, Y Wang… - Naunyn-Schmiedeberg's …, 2023 - Springer
… This narrative review aimed to explore the potential role and therapeutic mechanisms of
world traditional herbal active ingredients in sarcopenia-related animal models. A literature …

[HTML][HTML] Sarcopenia and muscle aging: a brief overview

T Dao, AE Green, YA Kim, SJ Bae… - Endocrinology and …, 2020 - synapse.koreamed.org
… There is still no accepted therapy for sarcopenia in humans. Here we provide a brief review
of the current state of research derived from various mouse models or human samples that …

[HTML][HTML] 66Mouse models of accelerated aging in musculoskeletal research for assessing frailty, sarcopenia, and osteoporosis-a review

D Yılmaz, N Mathavan, E Wehrle, GA Kuhn… - Ageing Research …, 2023 - Elsevier
… Herein, this review focuses on relevant mouse models of musculoskeletal aging with … frailty,
osteoporosis, and sarcopenia. Among the discussed models, PolgA mice in particular exhibit …

Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia

A Börsch, DJ Ham, N Mittal, LA Tintignac… - Communications …, 2021 - nature.com
… Emergence of the sarcopenic phenotype during mouse aging To follow the natural development
of sarcopenia in male C57BL/6JRj mice, we comprehensively characterized changes in …

Doxorubicin causes cachexia, sarcopenia, and frailty characteristics in mice

PS Cella, RLN Matos, PC Marinello, JC Costa… - Plos one, 2024 - journals.plos.org
… provide a comprehensive assessment of the effects of doxorubicin treatment on cachexia, …
By replicating these aspects of cachexia in the animal model, our study provides valuable …

[HTML][HTML] Is dexamethasone-induced muscle atrophy an alternative model for naturally aged sarcopenia model?

BYH Wang, AWT Hsiao, N Wong, YF Chen… - Journal of Orthopaedic …, 2023 - Elsevier
evaluated that the dexamethasone-induced mouse model could be served as an alternative
model for primary sarcopenia… -induced mice can be used as an animal model when studying …