Mouse models of sarcopenia: classification and evaluation
W Xie, M He, D Yu, Y Wu, X Wang, S Lv… - … , sarcopenia and …, 2021 - Wiley Online Library
… animal models is particularly important. In this paper, we will review the different mouse models
of sarcopenia, … the pathophysiology of sarcopenia, and evaluate the different therapeutic …
of sarcopenia, … the pathophysiology of sarcopenia, and evaluate the different therapeutic …
[HTML][HTML] Two types of mouse models for sarcopenia research: senescence acceleration and genetic modification models
… mouse models in research may be relatively narrow, but there are mouse models that can
be reasonably used in sarcopenia … this review, we introduce accelerated senescence mouse …
be reasonably used in sarcopenia … this review, we introduce accelerated senescence mouse …
[HTML][HTML] Rodent model of muscular atrophy for sarcopenia study
… Therefore, when judged comprehensively, selecting an animal with an extreme-value after
evaluating skeletal muscle mass and grip strength, etc. in aging rodents is probably the most …
evaluating skeletal muscle mass and grip strength, etc. in aging rodents is probably the most …
Complementary combination of biomarkers for diagnosis of sarcopenia in C57BL/6J mice
… natural aging model, which may not reflect correctly sarcopenic … an evaluation of multiple
biomarkers for sarcopenia from … in a naturally aging mouse model. The digital biomarkers relate …
biomarkers for sarcopenia from … in a naturally aging mouse model. The digital biomarkers relate …
The potential of traditional herbal active ingredients in the treatment of sarcopenia animal models: focus on therapeutic effects and mechanisms
K Ding, W Jiang, J Zhangwang, Y Wang… - Naunyn-Schmiedeberg's …, 2023 - Springer
… This narrative review aimed to explore the potential role and therapeutic mechanisms of
world traditional herbal active ingredients in sarcopenia-related animal models. A literature …
world traditional herbal active ingredients in sarcopenia-related animal models. A literature …
[HTML][HTML] Sarcopenia and muscle aging: a brief overview
… There is still no accepted therapy for sarcopenia in humans. Here we provide a brief review
of the current state of research derived from various mouse models or human samples that …
of the current state of research derived from various mouse models or human samples that …
[HTML][HTML] 66Mouse models of accelerated aging in musculoskeletal research for assessing frailty, sarcopenia, and osteoporosis-a review
D Yılmaz, N Mathavan, E Wehrle, GA Kuhn… - Ageing Research …, 2023 - Elsevier
… Herein, this review focuses on relevant mouse models of musculoskeletal aging with … frailty,
osteoporosis, and sarcopenia. Among the discussed models, PolgA mice in particular exhibit …
osteoporosis, and sarcopenia. Among the discussed models, PolgA mice in particular exhibit …
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia
… Emergence of the sarcopenic phenotype during mouse aging To follow the natural development
of sarcopenia in male C57BL/6JRj mice, we comprehensively characterized changes in …
of sarcopenia in male C57BL/6JRj mice, we comprehensively characterized changes in …
Doxorubicin causes cachexia, sarcopenia, and frailty characteristics in mice
… provide a comprehensive assessment of the effects of doxorubicin treatment on cachexia, …
By replicating these aspects of cachexia in the animal model, our study provides valuable …
By replicating these aspects of cachexia in the animal model, our study provides valuable …
[HTML][HTML] Is dexamethasone-induced muscle atrophy an alternative model for naturally aged sarcopenia model?
BYH Wang, AWT Hsiao, N Wong, YF Chen… - Journal of Orthopaedic …, 2023 - Elsevier
… evaluated that the dexamethasone-induced mouse model could be served as an alternative
model for primary sarcopenia… -induced mice can be used as an animal model when studying …
model for primary sarcopenia… -induced mice can be used as an animal model when studying …