[HTML][HTML] Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration

K Bartlette, AM Carreau, D Xie, Y Garcia-Reyes… - Metabolism open, 2021 - Elsevier
… Given the extended period of elevated glucose concentrations in our … estimates of S I would
depend on protocol duration and that at least 4 h of data are required to accurately estimate

Estimating insulin sensitivity and β-cell function from the oral glucose tolerance test: validation of a new insulin sensitivity and secretion (ISS) model

J Ha, ST Chung, M Springer, JY Kim… - American Journal …, 2024 - journals.physiology.org
Oral minimal model-based estimates of insulin sensitivity in obese youth 818 depend on
oral glucose tolerance test protocol duration. Metabol Open 9: 100078, 2021. 819 …

β-Cell function and insulin sensitivity in youth with early type 1 diabetes from a 2-hour 7-sample OGTT

A Galderisi, C Evans-Molina, M Martino… - The Journal of …, 2023 - academic.oup.com
relying on glucose and insulin concentrations to estimate SI. … such as pubertal development
or BMI changes. The limited … on the reliability of the model-based estimates. However, the …

Metabolic and genetic determinants of glucose shape after oral challenge in obese youths: a longitudinal study

A Galderisi, D Tricò, C Dalla Man… - The Journal of …, 2020 - academic.oup.com
… the model-based OGTT-derived estimate of insulin secretion … of glucose tolerance as time
to glucose peak and glucose … with reduced insulin sensitivity (37), whereas in youth with …

The minimally-invasive oral glucose minimal model: Estimation of gastric retention, glucose rate of appearance, and insulin sensitivity from type 1 diabetes data …

E Faggionato, M Schiavon, L Ekhlaspour… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
… , which varies depending on the total amount of glucose in the stomach Qsto… insulin dosing
for fat and protein in type 1 diabetes: Application of a model-based approach to derive insulin

Estimation of glucose absorption, insulin sensitivity, and glucose effectiveness from the oral glucose tolerance test

D Stefanovski, DD Smiley, NM Punjabi… - The Journal of …, 2024 - academic.oup.com
… , which depends on the plasma concentration of insulin, I(t), … to estimating insulin sensitivity.
The unique aspect of this new model is that it adopts the gold standard oral glucose minimal

Early impairment of insulin sensitivity, β-cell responsiveness, and insulin clearance in youth with stage 1 type 1 diabetes

A Galderisi, A Moran, C Evans-Molina… - The Journal of …, 2021 - academic.oup.com
… index, that simply rely on fasting glucose and insulin (23), … we excluded the individual with
the BMI z-score of 1.25 and … (1) the use of a robust model-based assessment of the DI in this …

[PDF][PDF] … estimation of physiological parameters of the glucose-insulin regulatory system: a modeling approach for reduced-sampling oral glucose tolerance test data

LL DEL GIUDICE - 2022 - tesi.univpm.it
… , leads to reduced glucose transport into muscle cells and an increase in fat breakdown. This
insulin sensitivity or resistance. This analysis relies on data related to glucose and insulin

Techniques to Assess Insulin Action in Youth

SF Michaliszyn, S Arslanian - Insulin Resistance: Childhood Precursors of …, 2020 - Springer
… WBISI and clamp insulin sensitivity depends on gender, with … A model-based index of insulin
sensitivity (derived from the … of 185 overweight/obese youth with varying glucose tolerance, …

Comprehensive validation of fasting-based and oral glucose tolerance test–based indices of insulin secretion against gold standard measures

K Prystupa, R Renklint, Y Chninou, J Otten… - BMJ Open Diabetes …, 2022 - drc.bmj.com
… proposed to estimate insulin sensitivity and insulin secretion, … secretory dysfunction as
precursors of non-insulin-dependent … and insulin resistance in overweight Chinese adolescents