Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles
D Olmeda, D Cerezo-Wallis, E Castellano-Sanz… - Advanced Drug Delivery …, 2021 - Elsevier
… Therefore, there is great interest in visualizing the lymphatic vasculature in vivo. Here, we
review imaging tools and mouse models used to analyze the lymphatic vasculature during …
review imaging tools and mouse models used to analyze the lymphatic vasculature during …
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes
N Trac, EJ Chung - Experimental Biology and Medicine, 2021 - journals.sagepub.com
… to have phagocytic capacity and affect nanoparticle clearance in vivo. Macrophages can be
… physiological barriers described in this section, nanoparticles can enter the lymphatic system …
… physiological barriers described in this section, nanoparticles can enter the lymphatic system …
Nanoparticle-based approaches to target the lymphatic system for antitumor treatment
… NPs and adopting various administration routes to facilitate lymphatic system uptake [20].
In addition, nanoparticle self-assembly in vivo has been employed for sustained drug delivery …
In addition, nanoparticle self-assembly in vivo has been employed for sustained drug delivery …
Lymphatic targeting for therapeutic application using nanoparticulate systems
… evaluating in vivo distribution characteristics or lymphatic delivery of … delivery of the
nanoparticle in lymphatic system. Irrespective … Normal physiological features of lymphatic system …
nanoparticle in lymphatic system. Irrespective … Normal physiological features of lymphatic system …
Targeting lymphatics for nanoparticle drug delivery
J McCright, R Naiknavare, J Yarmovsky… - Frontiers in …, 2022 - frontiersin.org
… In this review, we discuss the physiology of lymphatic vessels and mechanisms used in the
… formulations reached lymph nodes and were more effective in elucidating in-vivo immune …
… formulations reached lymph nodes and were more effective in elucidating in-vivo immune …
Therapeutic delivery to the brain via the lymphatic vasculature
… (ICG)-loaded PLGA nanoparticles as a model, we show that … a high colloidal stability in
physiological medium due to the … that nanoparticles can diffuse through the lymphatic vessels …
physiological medium due to the … that nanoparticles can diffuse through the lymphatic vessels …
Simulation of the in vivo fate of polymeric nanoparticles traced by environment-responsive near-infrared dye: A physiologically based pharmacokinetic modelling …
… , owing to the complicated in vivo transport mechanisms involving nanoparticles, including
… , lymphatic transport, and changes in physical properties. In our study, five nanoparticle …
… , lymphatic transport, and changes in physical properties. In our study, five nanoparticle …
[HTML][HTML] Imaging technology of the lymphatic system
AK Polomska, ST Proulx - Advanced drug delivery reviews, 2021 - Elsevier
… of basic anatomy and physiology and in our understanding of … In vivo imaging of the lymphatic
system in animal models has … The optimal size of nanoparticles for SLN imaging was found …
system in animal models has … The optimal size of nanoparticles for SLN imaging was found …
The bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery
… and NIR imaging in vivo after dorsal foot injection of PL(I/D)NPs. b Representative fluorescence
and 3D reconstructed CT images of superficial lymphatics with PL(I/D)NPs in vivo after …
and 3D reconstructed CT images of superficial lymphatics with PL(I/D)NPs in vivo after …
Nano lipid based carriers for lymphatic voyage of anti-cancer drugs: An insight into the in-vitro, ex-vivo, in-situ and in-vivo study models
… The flow of lymph from the lymphatic vessels is unidirectional … Hence, the lipid nanoparticles
with particle size in the range … simulate in-vivo physiological conditions [112]. Now, this …
with particle size in the range … simulate in-vivo physiological conditions [112]. Now, this …