TNF-alpha inhibitors and ustekinumab for the treatment of psoriasis: Therapeutic utility in the era of IL-17 and IL-23 inhibitors

JJ Hong, EK Hadeler, ML Mosca… - Journal of psoriasis …, 2022 - journals.sagepub.com
… number of medical indications besides psoriasis. Here, we review the specific niches where
TNF-α inhibitors and ustekinumab may have utility compared to other biologic therapies. …

[PDF][PDF] Evaluation of ustekinumab treatment in psoriasis and the potential effect of metabolic syndrome on treatment response: A single center retrospective study

O Kutlu, HM Eksioglu - Int J Res Dermatol, 2020 - researchgate.net
… of psoriasis, IL-12/23 inhibitors were developed for treatment of … The cytokine dysregulation
of TNF-alpha, IL-6, and, IL-17 … the therapeutic potential of ustekinumab in psoriasis vulgaris …

Ustekinumab: In Psoriasis and Beyond—A Derm atological Perspective

AK Bubna, V Viplav - Journal of Pharmacology and …, 2024 - journals.sagepub.com
utility of ustekinumab in non-pustular palmoplantar psoriasis … after 172 weeks of ustekinumab
therapy, and rapid improvement … the utility of other biological drugs with ustekinumab in the …

Past, present and (foreseeable) future of biological anti-TNF alpha therapy

GM Leone, K Mangano, MC Petralia, F Nicoletti… - Journal of Clinical …, 2023 - mdpi.com
… ’s disease, plaque psoriasis and pediatric ulcerative colitis. … , their utility as diagnostics or
therapeutics will grow as well. … pegol (Cimzia) and etanercept (Enbrel). Several studies have …

Risk of developing melanoma with systemic agents used to treat psoriasis: a review of the literature

A Semaka, TG Salopek - Journal of Cutaneous Medicine and …, 2022 - journals.sagepub.com
… such that we now have a plethora of therapies at our disposal. … treatments, small molecule
drugs and biologics used in the … not report significant risk of melanoma for ustekinumab. Two …

Adalimumab, ustekinumab, and secukinumab in the management of hidradenitis suppurativa: a review of the real-life experience

F Martora, M Megna, T Battista, L Potestio… - Clinical, Cosmetic …, 2023 - Taylor & Francis
… or had contraindications to at least one anti-TNF-alpha. In this study, the … according to the
psoriasis therapeutic schedule of … pain/utility/handicap score decreased from 1 to 2. Citation78 …

Decrease in inflammation markers with ustekinumab treatment in moderate-severe psoriasis

B Taşkın, B Memet, E Vurgun, S Alper - Pamukkale Medical Journal, 2021 - dergipark.org.tr
… This study aimed to investigate the utility of these markers for … plaque psoriasis, who received
ustekinumab therapy were … such as IL-6 and TNF-alpha compared to NLR and that it was …

[HTML][HTML] Clinical outcomes of ustekinumab in inflammatory bowel disease

SK Gara, P Guntipalli, S Marzban, M Taqi, V Aryal… - Cureus, 2023 - ncbi.nlm.nih.gov
… Seven studies proved its role in psoriasis, axial … even with conflicting data regarding its
utility in clinical practice. The … that ustekinumab is more cost-effective in the TNF-alpha-inhibitor

[HTML][HTML] A Systematic Review Evaluating the Effectiveness of Several Biological Therapies for the Treatment of Skin Psoriasis

SA Alzahrani, FM Alzamil, AM Aljuhni, NA Al Thaqfan… - Cureus, 2023 - ncbi.nlm.nih.gov
… the psoriasis immune response [14]. Through the inhibition of IL-12 and IL-23, ustekinumab
… this research including “Psoriasis”, “biological treatment”, “TNF-alpha inhibitor”, “IL-12/IL-23 …

From bed to bench and back: TNF-α, IL-23/IL-17A, and JAK-dependent inflammation in the pathogenesis of psoriatic synovitis

E Silvagni, S Missiroli, M Perrone… - Frontiers in …, 2021 - frontiersin.org
… the treatment response to other bDMARDs, such as ustekinumab, but the evidence is mostly
available in psoriasis … The research utility of synovial biomarker discovery relies on the …