… free radical formations and protection of neurons. Therefore, … Parkinson’s disease is a
heterogenous disease varying in age, … disease requires to use of a variety of animal models. …

… More importantly, we showed that AS-IV protected against the loss of dopamine neurons
and behavioral deficits in the mouse model of PD, which companied by reduced accumulation …

… Therefore, the key to treating PD is to protect dopaminergic neurons and preserve the …
a classical MPTP-induced PD mouse model. MPTP induces nigrostriatal dopaminergic …

… animal models [9],[10], suggesting that RIP-1 activation may be involved in dopaminergic
neuron … have been shown to protect against neurodegenerative disorders by controlling energy …

… Consequently, our findings indicate that TRPV1 protects dopaminergic neurons from injury
… -related molecules in the PD animal model and DA neurons cultured in vitro. The assays …

… The observation that misfolded, fibrillar forms of aSYN can propagate from one cell to another
in PD animal models [10], has fueled the thought that also in humans toxic aSYN species …

… of iPSC-sEVs to rejuvenate the senescent BBB in naturally aging mice and then evaluated
the neuroprotective effects of iPSC-sEVs in aged stroke mice. Our results demonstrated that …

… neurons and in the regulation of synaptic transmission and plasticity. They have also been
shown to protect neurons from neurodegeneration in animal models … in Parkinson disease in …

… peppers, was seen to protect dopaminergic neurons in PD mouse models by supporting …
of cellular senescence, promoting tissue rejuvenation and potentially extending healthspan. …

… only limited success in rejuvenating mitochondrial function or in … decay, the results using
animal models and, in some instances … mitochondrial rejuvenating compounds for human use. …