miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS …

S He, Q Wang, L Chen, YJ He, X Wang… - Journal of Translational …, 2023 - Springer
… pathway involved in the protection of DA neurons in T-MSCs, … Next, we used MPTP to
create a PD mouse model 15 days … cells and facilitating their restoration and rejuvenation [45]. …

NLRP3 mediates the neuroprotective effects of SVHRSP derived from scorpion venom in rotenone-induced experimental Parkinson's disease model

Y Zhang, S Li, L Hou, M Wu, J Liu, R Wang… - Journal of …, 2023 - Elsevier
… The PD mouse model was induced by rotenone and the … Parkinson's disease (PD) is the
second most common … We recently found that SVHRSP could protect against dopaminergic …

[HTML][HTML] Photobiomodulation Therapy and Cell Therapy Improved Parkinson's Diseases by Neuro-regeneration and Tremor Inhibition

B Ahrabi, FST Mirakabad, S Niknazar… - Journal of Lasers in …, 2022 - ncbi.nlm.nih.gov
… A study showed that PBM (670 nm, 0.16 mW) in the acute MPTP mouse model protected
dopaminergic cells when used intracranially and intermittently, and when PBM (4 × 90 seconds …

Exploring the Efficient Natural Products for the Therapy of Parkinson's Disease via Drosophila Melanogaster (Fruit Fly) Models

W Zhang, Y Ju, Y Ren, Y Miao, Y Wang - Current Drug Targets, 2024 - ingentaconnect.com
… high-throughput animal model for studying various diseases and … Ginseng protein (GTP)
protects against mitochondrial … in transgenic Drosophila model of Parkinson's disease. ISRN …

Carnosine suppresses neuronal cell death and inflammation induced by 6-hydroxydopamine in an in vitro model of Parkinson's disease

M Kubota, N Kobayashi, T Sugizaki, M Shimoda… - PLoS …, 2020 - journals.plos.org
… be caused by loss of dopamine neurons in the substantia nigra and the … neuronal shedding
and microglial activation have also been observed in animal models of Parkinson's disease

… of AMPA receptor and its trafficking proteins in the hippocampus is associated with recognition memory impairment the rotenone-Parkinson's disease mouse model …

V Gupta, S Prasad - 2024 - researchsquare.com
protecting and treating the brain by restoring these proteins. Rotenone is recognised for its
ability to develop an effective model of Parkinson's disease … developed a PD mouse model by …

The Role of Astrocytes and Alpha-Synuclein in Parkinson's Disease: A Review

D Brash-Arias, LI García, CA Pérez-Estudillo… - NeuroSci, 2024 - mdpi.com
… in an in vivo mouse model with acute … to neuronal death, A2 astrocytes produce antioxidant
molecules in response to oxidative stress and protect dopaminergic neurons in rat PD models

Are ion channels potential therapeutic targets for Parkinson's disease?

NH Daniel, A Aravind, P Thakur - Neurotoxicology, 2021 - Elsevier
… Blocking neuronal Cav channels protect neurons but the … mouse model of PD is reported
to have an increased expression of Kv2.1, a delayed rectifying channel in the SN DA neurons. …

Potassium channels and their emerging role in parkinson's disease

L Zhang, Y Zheng, J Xie, L Shi - Brain research bulletin, 2020 - Elsevier
… -ATP channels has protective effects on DA neurons in PD mouse models. The Kir6.2 knockout
can … the IRP-IRE regulatory system, thereby protecting SN DA neurons from MPTP attack. …

… mice with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-Induced Parkinson's disease by regulating the microbiota-metabolite–brain axis and fibroblast growth factor …

C Chu, T Li, L Yu, Y Li, M Li, M Guo… - … of Agricultural and …, 2023 - ACS Publications
… (17) According to a previous method, a PD-like mouse model was … -21 levels in the mouse
serum and midbrain, protected dopaminergic … Parkinson disease and the gut: new insights into …