… PDX models have been shown to recapitulate the landmark genomic and histopathological
features of prostate cancer and are capable of maintaining their fidelity after multiple rounds …

… AVPC spans a spectrum of histological appearances, from poorly … somatic alteration landscape
in early-onset prostate cancer. … The association between germline BRCA2 variants and …

… least 2 relatives with early-onset (<55 years old) disease (9% … World Health Organization
(WHO) reviewed the histological … , necessitating a response by the Pathology community. Thus, …

… The association with sebaceous carcinoma is weakest and … in conjunction with family history
and germline genetic testing. … that is characterized by defects in MMR genes and early-onset …

… were collected using medical records and pathology reports. … was used to assess the
associations of carrier status with those … and having a daughter with early-onset breast cancer. On …

… risk of early-onset breast cancer (BC) and ovarian cancer (… carcinoma, pancreatic cancer,
or metastatic prostate cancer at … BRCA1/2 pathogenic mutations, tumor pathology, and loss of …

… small families or apparently isolated early-onset GC cases … family history, patient's age of
onset, tumours' histological … described to date display mainly DGC, and a clear association with …

… The prevalence of histological prostate cancer is remarkably … , and their association with the
etiology of prostate cancer and … lysis have shown that early onset of prostate cancer may be …

… , 492 cancer cases were reported after histological verification … use of early-onset PC patients
(before the age of 51 years). … at the Jamaica Cancer Society screening clinic from 1995 to …

… in advanced disease is explained by their association with a … disease in three consecutive
generations and (c) early-onset … with a limited tumor volume and low histopathological grade […