Pharmacological anti-remodelling effects of disease-modifying drugs in heart failure with reduced ejection fraction

M Correale, P Mazzeo, L Tricarico, F Croella… - Clinical Drug …, 2022 - Springer
… an acceptable forward flow from the left ventricle [6]. Major … trend on ventricular remodelling
[45]: after 48 weeks, both captopril and … Mineralocorticoid hormones exert essential effects on …

Characterization of ACE inhibitory peptide from Cassia tora L. globulin fraction and its antihypertensive activity in SHR

P Chen, Y Ren, Y Zhang, Y Liu, H Shi, Z Chen… - … Food Research and …, 2022 - Springer
left ventricle remodeling was prevented in the TTPSY group. Captopril showed cardio-improvement
effects … , which obviously decreased mean arterial blood pressure, was detected in …

Cardiac Involvement: Evaluation and Management

L Gargani, M Mazzola, SJ Shah - Scleroderma: From Pathogenesis to …, 2024 - Springer
… the left ventricle together is associated with a defective cardiac … , right ventricular function,
and pulmonary hypertension. Many … , is necessary in patients with SSc when the diagnoses of …

Diosmetin ameliorates vascular dysfunction and remodeling by modulation of Nrf2/HO-1 and p-JNK/p-NF-κB expression in hypertensive rats

S Meephat, P Prasatthong, P Potue, S Bunbupha… - Antioxidants, 2021 - mdpi.com
… (NO) is an essential vasodilator released from the vascular … disorders and improves left
ventricular dysfunction and … In this study, captopril was used as a positive control agent. …

[HTML][HTML] Emerging therapies for right ventricular dysfunction and failure

A Klinke, T Schubert, M Müller… - Cardiovascular …, 2020 - ncbi.nlm.nih.gov
pulmonary arterial hypertension (PAH), where it is not possible to discern pulmonary vascular-
and RV-directed effects … Therapy effective for left heart failure is not applicable to RHF, eg, …

Effects of Long-Term Administration of Bovine Bone Gelatin Peptides on Myocardial Hypertrophy in Spontaneously Hypertensive Rats

S Cao, X Wang, L Xing, W Zhang - Nutrients, 2023 - mdpi.com
effect of high-dose BGP treatment on left ventricular protein evolution in SHR rats was similar
to captopril … It is well known that SHR rats with essential hypertension are one of the most …

Treatment of Heart Failure with reduced Ejection Fraction in 2022: The Essential Pillars

MG Bonatto, AO Coiradas… - ABC Heart Fail …, 2022 - abcheartfailure.org
… long-term harmful effects on cardiac structure and function.… Mechanisms that can be listed
include improved left ventricle … endothelial function and reduced arterial blood pressure), …

… -Converting Enzyme Inhibitor (ACEI) and Angiotensin Receptor Blocker (ARB) for Heart Failure Treatment in Congenital Heart Diseases with Left-to-Right Shunt

A Utamayasa, MA Rahman, T Ontoseno - The Indonesian Biomedical …, 2020 - inabj.org
… This study aimed to compare the impact of captopril, one of … left ventricular end-diastolic
volume (LVEDV), left ventricular … hypertrophy and function in essential hypertension. Adv Ther…

Identification of celastrol as a novel therapeutic agent for pulmonary arterial hypertension and right ventricular failure through suppression of Bsg (Basigin)/CyPA …

R Kurosawa, K Satoh, T Nakata, T Shindo… - … , and Vascular …, 2021 - Am Heart Assoc
… cardiac fibrosis and failure in the left ventricle in response to … Also, Bsg is an essential
receptor for CyPA (cyclophilin A) that … To evaluate the effect of celastrol on RV itself, we treated …

Right heart failure in pulmonary hypertension

SJ Cassady, GV Ramani - Cardiology clinics, 2020 - cardiology.theclinics.com
… on the pulmonary vasculature, with only secondary effects on … the left ventricle and decreasing
left ventricular filling through … studies are essential in the management of PH in RV failure. …