Role of curcumin in ameliorating hypertension and associated conditions: a mechanistic insight

P Joshi, S Joshi, DK Semwal, K Verma… - Molecular and Cellular …, 2022 - Springer
… The kidney performs an essential functionfunctionality allows cysteine residue, effect
separation of Nrf2 from Keap1 and its translocation to the nucleus. Glomerular high blood pressure

The RAAS goodfellas in cardiovascular system

I Caputo, G Bertoldi, G Driussi, M Cacciapuoti… - Journal of Clinical …, 2023 - mdpi.com
… associated with the induction of essential hypertension [45]. … where inhibition of ACE by
captopril led to an upregulation of … infarct size and left ventricular function in isolated perfused …

Linggui Zhugan decoction delays ventricular remodeling in rats with chronic heart failure after myocardial infarction through the Wnt/β-catenin signaling pathway

M Yang, H Wu, H Qian, D Li, H Xu, J Chen, J Zhong… - Phytomedicine, 2023 - Elsevier
… Therefore, it is crucial to find new ways to improve the … and LVIDs and found that the left
ventricle of rats in each HF group had … the same effect as captopril in improving cardiac function. …

Snake Venom Components as Therapeutic Drugs in Ischemic Heart Disease

E Messadi - Biomolecules, 2023 - mdpi.com
… drug, captopril, against hypertension based on the structure of … Initially indicated for the
treatment of arterial hypertension, … chronic HF with reduced left ventricular ejection function [180]. …

Targeting liver angiotensinogen using a GalNAc-siRNA improves cardiac remodeling in spontaneously hypertensive rats

J Johannes Wikstrom, J Liang, H Cao… - European Heart …, 2023 - academic.oup.com
… We showed the long-term effects of a GalNAc-siRNA … blood pressure and left ventricular
hypertrophy. Compared to daily oral administration of Captopril and its effect on blood pressure

[PDF][PDF] Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-p1 and MMPs Protein Expression

P Maneesai, S Bunbupha, P Potue, T Berkban… - … Intake and Hypertension - mdpi.com
… ), and fibrosis in the left ventricular and vascular remodeling, ie, increases … effects of captopril
in nitric oxide-deficient hypertensive rats, ie, lowering … A new model of arterial hypertension. …

[HTML][HTML] Effect of sacubitril/valsartan on the hypertensive heart in continuous light-induced and lactacystin-induced pre-hypertension: Interactions with the renin …

F Simko, P Stanko, K Repova, T Baka… - Biomedicine & …, 2024 - Elsevier
… /valsartan or valsartan are able to prevent left ventricular (LV) fibrotic remodelling and
dysfunction in two experimental models of pre-hypertension induced by continuous light (24 hours/…

Ameliorative effect of mussel-derived ACE inhibitory peptides on spontaneous hypertension rats

Q You, X Sun, J Chen, J Yu, Y Wei - European Journal of Nutrition, 2023 - Springer
essential hypertension [22]. After one week of adaptation, the … Hypertension causes left
ventricular diastolic dysfunction, … group, indicating that captopril had toxic side effects on the liver. …

Renin angiotensin blockers and cardiac protection: from basics to clinical trials

BI Lévy, JJ Mourad - American Journal of Hypertension, 2022 - academic.oup.com
… The development of captopril, the first oral active angiotensin-… treatment of arterial hypertension,
heart failure, myocardial … and MI in hypertensive patients with left ventricular hypertrophy. …

[HTML][HTML] Comparative evaluation of captopril, spironolactone, and carvedilol effect on endothelial function in breast cancer women undergoing chemotherapy

SMH Jazi, F Tayebi, Z Teimouri-Jervekani… - Advanced Biomedical …, 2023 - journals.lww.com
… improving endothelial function. This study aimed to evaluate the effect of the combination
of Spironolactone, Carvedilol, and Captopril on endothelial function in breast cancer patients. …