Genetic relationships between attention-deficit/hyperactivity disorder, autism spectrum disorder, and intelligence

S Rao, A Baranova, Y Yao, J Wang, F Zhang - Neuropsychobiology, 2022 - karger.com
… In summary, our findings suggest that ADHD is associated with a reduced set of INT-associated
variants and the over-representation of low-INT alleles among its risk variants, whereas …

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

M Mattheisen, J Grove, TD Als, J Martin, G Voloudakis… - … genetics, 2022 - nature.com
… 34,646 genes and isoforms tested), we identified five genes or … genes or isoforms that were
significant at a false discovery … dissect the genetic architecture across the ASD and ADHD

Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder

KS O'Connell, A Shadrin, S Bahrami, OB Smeland… - Molecular …, 2021 - nature.com
… In addition, it should be noted that there is a possibility that our findings of shared genetic
loci between ADHD and BD may be the result of bias from misdiagnosis in the original GWAS …

ADHD: progressing from genetic discoveries to biological insights

A Thapar - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
Attention deficit hyperactivity disorder (ADHD) is one of the most heritable of all neuropsychiatric
disorders (1)… Gaining insight into the pathophysiology that underlies ADHD represents a …

Elevated risk of attention deficit hyperactivity disorder (ADHD) in Japanese children with higher genetic susceptibility to ADHD with a birth weight under 2000 g

MS Rahman, N Takahashi, T Iwabuchi, T Nishimura… - BMC medicine, 2021 - Springer
… Nevertheless, our findings on the higher severity of ADHD traits and birth weight under
2000 g have clinical importance. This is because the percentages of children born with birth …

[HTML][HTML] DAT1 gene methylation as an epigenetic biomarker in attention deficit hyperactivity disorder: A commentary

E Tonelli, E Pascale, M Troianiello, C D'Addario… - … in Genetics, 2020 - frontiersin.org
… for the diagnosis of ADHD, some research has focused on … on the same strand of the gene
are important: also the M1-cos … on the strand of the gene is associated with ADHD (or its relief)…

Genetic influence on efficacy of pharmacotherapy for pediatric attention-deficit/hyperactivity disorder: overview and current status of research

NA Elsayed, KM Yamamoto, TE Froehlich - CNS drugs, 2020 - Springer
… This article reviews childhood ADHDgene investigations of methylphenidate and
atomoxetine response, with a smaller number investigating pharmacokinetic candidate genes and …

Effects of the dopamine transporter gene on neuroimaging findings in different attention deficit hyperactivity disorder presentations

A Bacanlı, G Unsel-Bolat, S Suren, KU Yazıcı… - Brain Imaging and …, 2021 - Springer
findings: 1) The DAT1 gene is 10R homozygous for differentiated brain activation in ADHD
… We hypothesized that if the DAT1 gene has different clinical effects on ADHD symptoms, the …

Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation

SJ Goodman, CL Burton, DT Butcher, MT Siu… - … disorders, 2020 - Springer
… Both ADHD and OCD have been the focus of considerable genetic research, including a …
Taken together with our findings, these results suggest that ADHD may be a more distinctive …

… cause a genetic disorder characterised by developmental delay/intellectual disability and a spectrum of neurobehavioural phenotypes including autism and ADHD

JL Granadillo, APA Stegmann, H Guo, K Xia… - … of medical genetics, 2020 - jmg.bmj.com
… detailed clinical and molecular findings in 17 patients with … autism and attention deficit and
hyperactivity disorder (ADHD). … , six patients had additional genetic findings, which possibly …