… mass due to a lack of cell proliferation, and impaired insulin secretion in adult life (12).
Furthermore, in adult islets, β1-integrin has proven to be important for beta-cell survival, insulin …

… of beta-cell β1 integrin expression is critical during the … and proliferation were observed in
fetal MIPβ1KO mice, downstream β1 integrin signaling pathways involved in cell proliferation …

… , αv, β1, β3, and β5 integrin subunits in mature human islets, while β1 is known to play a
pivotal role in regulating β-cell mass … signals that influence β-cell proliferation and function. The …

… pancreas, interaction between the ECM and islet cells via adhesion-mediated integrin
signaling has been shown to play a crucial … subunit as well as both the β1 and β5 but not the β3 …

… insulin secretion, and β-cell proliferation. This review focuses … that pericytes play a vital role
in regulating β-cell function and … well as β-cell expansion (70), furthering the evidence that β1 …

… in expansion of the β-cell mass during pregnancy in the rat. … αV, β1, β5, β6 and β8 are
abundant in rat β-cells.12 Several studies have shown that integrin β1 plays a crucial role in β-cell …

… We hypothesized that β1 integrin played an important role in the survival of ECM-adjacent …
pancreatic β cell cancer, genetic ablation of β1 integrin led to reduced tumor cell proliferation …

… β-cell proliferation plays an important role in maintaining β-cell mass and function, and in
improving pancreatic β-cell … The levels of Integrin α3, α5 and β1 were higher in cells cultured on …

… plays an important role in tissue repair, cell proliferation, and … Collagen I promotes β cell
proliferation, viability, and insulin … for collagenase G in pancreatic islet isolation Citation8,Citation…

… data suggest that integrin β1 inhibition could reduce pancreatic cancer cell proliferation and
… protein associated with integrin β1 and is important for integrin clustering and signaling. One …