Recent Applications and Future Perspectives of Chemiluminescent and Bioluminescent Imaging Technologies

IM Mostafa, A Abdussalam, YT Zholudov… - Chemical & …, 2023 - ACS Publications
… generate and emit light. The BL reaction usually needs a luciferase, its luciferin substrate,
and an … One of the first luciferin structures discovered was d-luciferin which was discovered in …

Deconstructing bioluminescence: from molecular detail to in vivo imaging.

ST Adams Jr - 2020 - repository.escholarship.umassmed …
… that enzymes capable of forming an AMP ester of luciferin should give rise to luciferase
activity, where the subsequent light emission chemistry is largely directed by the luciferin ester. …

Portable light detectors for bioluminescence biosensing applications: A comprehensive review from the analytical chemist's perspective

MM Calabretta, A Lopreside, L Montali, M Zangheri… - Analytica Chimica …, 2022 - Elsevier
… on different luciferases and luciferin analogues with a wide range of applications spanning
… toxicity sensors for measuring chemicals with different mode of action (paraquat, mitomycin C …

… brightness and spectral properties of click beetle and firefly luciferases using luciferin analogues: identification of preferred pairings of luciferase and substrate for in …

G Zambito, N Gaspar, Y Ridwan, MP Hall, C Shi… - Molecular Imaging and …, 2020 - Springer
… BLI applications. In addition, our findings revealed that depending on the luciferase/luciferin
pair, a … The aim of this study was to evaluate in vitro and in vivo light emission and spectral …

Copper‐mediated oxidation of imidazopyrazinones inhibits marine luciferase activity

JJ O'Sullivan, VJ Lee, MC Heffern - Luminescence, 2023 - Wiley Online Library
… intense luminescence relative to firefly luciferin/luciferase. … marine luciferases also exhibiting
marked decreases in light … from a luciferase interaction but rather the chemical oxidation …

Bioluminescent Antibodies through Photoconjugation of Protein G–Luciferase Fusion Proteins

SFA Wouters, WJP Vugs, R Arts… - … chemistry, 2020 - ACS Publications
… –luciferase conjugates starting from commercially available monoclonal antibodies. Our
approach uses fusion proteins consisting of the bright blue light-… other luciferaseluciferin pairs …

Biosensing firefly luciferin synthesis in bacteria reveals a cysteine-dependent quinone detoxification route in Coleoptera

DR de Souza, JR Silva, A Moreira, VR Viviani - Scientific Reports, 2022 - nature.com
… a benzothiazolic luciferin, MgATP, O 2 and 60 kDa luciferases … The chemical composition
and properties of firefly luciferin … , fluorescence of the samples under UV light irradiation (Fig. 3)…

[HTML][HTML] Bioluminescence sensor: enzymes, reaction and utilization as an energy source

B Yağdıran, S Ersoy, BN Gültekin… - Journal of Mechatronics …, 2022 - extrica.com
… The blue-green light emitted by some creatures living in the … oxidation of luciferin in the
presence of the luciferase enzyme. … light emitted from a non-biological source due to a chemical

The role of protein globule in firefly luciferase catalysis

NN Ugarova, GY Lomakina - Photochemistry and Photobiology, 2024 - Wiley Online Library
luciferinluciferase systems are unique, highly efficient converters of energy of biochemical
processes into light… classical organic chemistry, ketones, in the alpha position of which there is …

Photochemistry, chemiluminescence and dark photochemistry: computational advances (2018–2019)

D Roca-Sanjuán, J Carmona-García, BW Ding… - 2020 - books.rsc.org
… -state chemistry, the bio/chemiluminescence mechanism of … and the luciferin oxygenation
in luciferase for the first time. … modifying luciferin or luciferase to obtain near-infrared light