Signaling mechanisms and their regulation during in vivo or in vitro maturation of mammalian oocytes
P Strączyńska, K Papis, E Morawiec… - Reproductive Biology …, 2022 - Springer
… two-way axis of communication between the oocyte and somatic cells in mammals [36, 89]. …
activity [95]. This research confirms earlier observations on key role of gap junctions in cAMP …
activity [95]. This research confirms earlier observations on key role of gap junctions in cAMP …
cAMP modulators before in vitro maturation decrease DNA damage and boost developmental potential of sheep oocytes
DA Medina-Chávez, I Sánchez-Ajofrín, P Peris-Frau… - Animals, 2021 - mdpi.com
… The cGMP produced diffuses into the oocyte through gap junctions and inhibits the activity of
… To the best of our knowledge, this is the first study to examine the effect of cAMP modulators …
… To the best of our knowledge, this is the first study to examine the effect of cAMP modulators …
Approaches to oocyte meiotic arrest in vitro and impact on oocyte developmental competence
D Richani, RB Gilchrist - Biology of Reproduction, 2022 - academic.oup.com
… before in vitro maturation (IVM) improves oocyte developmental … of cAMP level within the
oocyte (box: [cAMP] modulators), … monkey and human [13, 16, 19, 27–36]. Chemical inhibition of …
oocyte (box: [cAMP] modulators), … monkey and human [13, 16, 19, 27–36]. Chemical inhibition of …
Cyclic AMP mediates ovine cumulus–oocyte gap junctional function via balancing connexin 43 expression and phosphorylation
Y Zhao, E Namei, B Yang, X Bao, W Sun… - Endocrine …, 2023 - ec.bioscientifica.com
… phosphorylation on specific sites during in vitro maturation (IVM) (… to the activation of PKA
activity. Subsequently, it regulates … cAMP modulators significantly increased the functional gap …
activity. Subsequently, it regulates … cAMP modulators significantly increased the functional gap …
Modulation of phosphatidylinositol 3-kinase activity during in vitro oocyte maturation increases the production of bovine blastocysts
JL Pereira, AG Curcio, LM Barroso… - Zygote, 2020 - cambridge.org
… High intra-oocyte concentrations of cAMP maintain the oocyte … However, during in vitro
maturation (IVM), the activity of various … effect of PI3K activity regulation on MPF activity, kinetics of …
maturation (IVM), the activity of various … effect of PI3K activity regulation on MPF activity, kinetics of …
Effect of Cyclic Adenosine Monophosphate on Connexin 37 Expression in Sheep Cumulus-Oocyte Complexes
M Zhao, G Subudeng, Y Zhao, S Hao, H Li - Journal of Developmental …, 2024 - mdpi.com
… of cAMP in multi-species oocytes during in vitro maturation can … explored the possible effects
of cAMP modulators on the … of cAMP on PKA activity and significantly downregulating the …
of cAMP modulators on the … of cAMP on PKA activity and significantly downregulating the …
Effects of cyclic adenosine monophosphate modulators on maturation and quality of vitrified-warmed germinal vesicle stage mouse oocytes
D Lee, HH Lee, JR Lee, CS Suh, SH Kim… - Reproductive Biology and …, 2020 - Springer
… monophosphate (cAMP) modulators to in vitro maturation (IVM… The elevated cAMP inhibits
the activity of protein kinase A, … process of F-actin and microtubule [35,36,37]. Therefore, it is …
the activity of protein kinase A, … process of F-actin and microtubule [35,36,37]. Therefore, it is …
Melatonin improves the maturation and developmental ability of bovine oocytes by up-regulating GJA4 to enhance gap junction intercellular communication
T Hao, X Xu, H Hao, W Du, Y Pang… - … and Development, 2021 - CSIRO Publishing
… bovine oocytes, and isoprenaline (enhancer of gap junctional … investigate the effect of MT
on GJIC activity in bovine oocytes. … effect of MT on oocyte quality during IVM, the cAMP level in …
on GJIC activity in bovine oocytes. … effect of MT on oocyte quality during IVM, the cAMP level in …
The ERβ-cAMP signaling pathway regulates estradiol-induced ovine oocyte meiotic arrest
B Yang, Y An, Y Yang, Y Zhao, K Yu, Y Weng, C Du… - Theriogenology, 2024 - Elsevier
… the IVM of oocytes, IVM is still less efficient than in vivo maturation [3]… levels in HeLa cells
and stimulated the transcriptional activity … monophosphate modulators during in vitro maturation …
and stimulated the transcriptional activity … monophosphate modulators during in vitro maturation …
Effects of cyclic adenosine monophosphate modulating agents during oocyte pre-maturation and the role of melatonin on in vitro maturation of bovine cumulus-oocyte …
BR Silva, LG Barrozo, DR Nascimento, FC Costa… - Animal Reproduction …, 2023 - Elsevier
… the effects of different combinations of cAMP modulating agents … collected from bovine
ovaries (n = 36) and pre-matured in TCM-… Mitochondrial activity in matured oocytes with different …
ovaries (n = 36) and pre-matured in TCM-… Mitochondrial activity in matured oocytes with different …