… approaches, 3D culture appeared to be a promising method to … drug development in oral
cancer is conventional 2D in vitro … The 3D in vitro models incorporate co-culture of cancer cells …

… gels, for the 3D co-culture of PDAC cells with myeloid cells over 14-28 … culture models can
aid drug discovery and biological … Although hedgehog inhibitors had promising results at the …

… models for anti-cancer drug screening due to their metabolic … model for cancer research
because they can co-culture a … a promising method to expand the diameter of tumor spheroids in …

… In spite of having early encouraging response with … scaffold-free approach to form monoculture
as well as coculture spheroids [… 3D culture model in OV-MZ-6 and SKOV-3 ovarian cancer …

… cancer models such as 3D cultures and organoid models are … of cancer behavior and
effective drug development. [ 129 ] … , on cocultured human hepatoma (HepG2) and glioma cell …

… valuable insights for cancer research and drug development. This … cancer progression and
drug screening for solid tumors [99]. … showed a good representation of the primary tumor and …

… 3D oncospheres confirms that NUDT5 is a promising target for drug discovery since it is an
upstream regulator of tumor … heterogeneous cell–cell relationships, as well as the coculture of …

… tumor-associated cells, which further increases the predictive value of 3D models, eg, for
drug development… not only on 3D models but also on 3D co-culture models to identify …

… Co-culture is possible from the scaffold culture, but cell … 3D cell culture system holds a
prodigious promise for drug … stir towards 3D drug discovery in the period of precision medicine. A …

… their analysis were summarized and the application of 3D tumor spheroid in specific drug
screening and in the elucidation of drug resistance mechanism was also provided. Despite the …