Aqueous humour outflow imaging: seeing is believing

JY Lee, G Akiyama, S Saraswathy, X Xie, X Pan… - Eye, 2021 - nature.com
… be stitched back together to generate an in situ outflow cast. … were developed to visualize
the actual flow of aqueous humour. … -dependent structural TM motion in enucleated non-human

Detailed 3D micro-modeling of rat aqueous drainage channels based on two-photon imaging: Simulating aqueous humor through trabecular meshwork and …

J Zhang, X Qian, H Zhang, H Chu, H Xu… - Medical & Biological …, 2022 - Springer
… In addition, TPM can acquire subcellular structures in situ without the need for tissue fixation
… rat eye is much smaller than that in humans (approximately 0.5 mm in human eyes) [35]. In …

How many aqueous humor outflow pathways are there?

C Costagliola, R Dell'Omo, L Agnifili, S Bartollino… - Survey of …, 2020 - Elsevier
… In humans, the outflow resistance occurs primarily within the … Aqueous humor (white
arrows) flows from the anterior chamber … With 3D visualization, the cross-sectional area is now …

Aqueous outflow imaging techniques and what they tell us about intraocular pressure regulation

JA Lusthaus, TZ Khatib, PAR Meyer, P McCluskey… - Eye, 2021 - nature.com
… be achieved with direct visualisation of aqueous drainage. We … from an actively perfused in
situ human eye imaged with SD-… 3D micro-CT showed that SC was attenuated superiorly, but …

Imaging Aqueous Outflow

RT Loewen, S Waxman, H Kollech… - Advances in Ocular …, 2020 - Springer
… The flow of aqueous humor is difficult to study due to its low … to visualize uveoscleral, including
uveolymphatic, outflow. A … Loewenstein characterized the human outflow system in more …

Segmental biomechanics of the normal and glaucomatous human aqueous outflow pathway

A Karimi, S Khan, R Razaghi, M Aga, SM Rahmati… - Acta Biomaterialia, 2024 - Elsevier
… some that work on aqueous humor outflow through the conventional … 1 to provide a clearer
visualization of the anatomical position … The in situ Young's modulus of SC endothelial cells of …

Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis

T van Zyl, W Yan, A McAdams… - Proceedings of the …, 2020 - National Acad Sciences
… in the human outflow pathways. (A) Clustering of 24,023 single-cell expression profiles from
human TM and associated structures visualized by t-… Human tissue used for IHC and in situ

Biomechanical properties of the trabecular meshwork in aqueous humor outflow resistance

VK Raghunathan - Ocular Rigidity, Biomechanics and Hydrodynamics of …, 2021 - Springer
… system and its influence on IOP have been studied in humans … to move towards the use of
3D scaffolds or cell derived matrices to … Computational modeling of TM behavior will provide …

Cellular Mechanisms Regulating Conventional Outflow of Aqueous Humor

WD Stamer, CR Ethier - Albert and Jakobiec's Principles and Practice of …, 2022 - Springer
… has been visualized in real time using OCT-A (“aqueous … the hope that they will differentiate
in situ and/or release beneficial … pattern and morphology in human eyes. Invest Ophthalmol …

3D numerical investigation of the fluid mechanics in a partially liquefied vitreous humor due to saccadic eye movement

J Bayat, H Emdad, O Abouali - Computers in Biology and Medicine, 2020 - Elsevier
… μL per minute secretions of aqueous humor into the posterior … flow dynamics of human
vitreous humor as a viscoelastic substance in linear and non-linear regime for different 2D and 3D