Efficacy of liposome‐encapsulated 4nbutylresorcinol and resveratrol cream in the treatment of melasma

SH Kwon, JH Yang, JW Shin, KC Park… - Journal of Cosmetic …, 2020 - Wiley Online Library
… have been shown to inhibit UV-induced pigmentation.9, 10 Since … tyrosinase levels, we
evaluated efficacy and safety of a … , 4nBR, a strong tyrosinase inhibitor, could work in combination …

The top 10 cosmeceuticals for facial hyperpigmentation

T Searle, F Al‐Niaimi, FR Ali - Dermatologic Therapy, 2020 - Wiley Online Library
… 50 000 other possible tyrosinase inhibitors tested. Thiamidol … be the most effective
combination in treating pigmentation in … treated melasma patients with twice daily 4-n-butylresorcinol

[HTML][HTML] Skin depigmenting agents in anti-aging cosmetics: A medicinal perspective on emerging ingredients

DISP Resende, MS Ferreira, JMS Lobo, E Sousa… - Applied Sciences, 2022 - mdpi.com
… 4-Butylresorcinol, also known as rucinol, is a highly effective … use of a 0.3% 4-n-butylresorcinol
cream instead of the widely … senile hyperpigmentation on the forearm were treated twice …

Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises

S Zolghadri, M Beygi, TF Mohammad… - Biochemical …, 2023 - Elsevier
… in the treatment of hyperpigmentation. In this review, we discuss the available strategies for
the management of hyperpigmentation with a focus on TYR inhibition. In addition, alternative …

[HTML][HTML] Comparative Studies on the Photoreactivity, Efficacy, and Safety of Depigmenting Agents

S Mota, GP Rosa, MC Barreto, J Garrido, E Sousa… - Pharmaceuticals, 2023 - mdpi.com
… , 4BR was the most effective compound inhibiting tyrosinase, … aimed at addressing
hyperpigmentation in the cosmetics … are the most potent and photostable tyrosinase inhibitors, …

Preparation and characterization of different supported 4-n-butylresorcinol nanoemulsions

M Li, W Shao, H Ren, X Li, M Yin, F Zhang, J Li… - 2024 - researchsquare.com
… widely used as effective inhibitors of tyrosinase production [2]… for treating hyperpigmentation,
including cosmetics, topical … . 4-n-butylresorcinol, a highly effective tyrosinase inhibitor for …

… of a skin whitening serum applied twice daily combined with a spot‐preventing SPF50+ sunscreen in healthy female subjects with melasma hyperpigmentation

M Cantelli, M Ferrillo, C Granger… - Journal of Cosmetic …, 2022 - Wiley Online Library
topical serum containing 4-n-butylresorcinol4-n-butylresorcinol (4nBR) inhibits melanogenesis
by enhancing proteolytic degradation of tyrosinase and inhibiting the activity of tyrosinase

Development of a Serum with 4-N-Butylresorcinol in The Etosome Vesicular System

WP Annissya, M Abdassah… - Jurnal Aisyah: Jurnal …, 2023 - aisyah.journalpress.id
… to be very effective as a human tyrosinase inhibitor with an … as well as the route of topical
administration, so a delivery form is … prevalence of hyperpigmentation in Indonesia is quite high, …

[HTML][HTML] Cosmeceuticals in hyperpigmentary disorders

S Kiruthika, J Sejal, V Keshavmurthy - Pigment International, 2023 - journals.lww.com
… [ 35 ] They found the test cream to be significantly better at … as 4-n-butylresorcinol are used
in hyperpigmented disorders. … in comparison to 50,000 other possible tyrosinase inhibitors

[HTML][HTML] Synthesis of Resorcinol Derivatives and their Effects on Melanin Production

Y Tokudome, T Hoshi, S Mori, I Hijikuro - Cosmetics, 2020 - mdpi.com
… or pigmentation disorders. … 4-n-butylresorcinol shows potent tyrosinase inhibitory effects at
lower doses [17]. Additionally, it exhibits TRP1 inhibitory effects, which results in the inhibition