Cardiovascular serotonergic system: Evolution, receptors, transporter, and function

G Soslau - … of Experimental Zoology Part A: Ecological and …, 2022 - Wiley Online Library
Serotonin, or 5-hydroxytryptamine (5-HT) is synthesized from … it pertains to function within
the cardiovascular system. … the 15 serotonin receptors and the serotonin transporter, SERT, has …

Cardiac roles of serotonin (5-HT) and 5-HT-receptors in health and disease

J Neumann, B Hofmann, S Dhein, U Gergs - International Journal of …, 2023 - mdpi.com
… that enteramine was chemically 5-hydroxytryptamine (5-HT) [1]. … into platelets via (serotonin
transporter) SERT (reviewed in [2,21])… might be altered in cardiovascular disease. The signal …

Serotonin: a platelet hormone modulating cardiovascular disease

M Rieder, N Gauchel, C Bode… - Journal of thrombosis and …, 2021 - Springer
… This review focuses on the role of serotonin in … up by platelets via the 5-HT transporter SERT
[14]. Platelets, as the … When the serotonin transporter is lacking, an agonist-induced Ca 2+ …

Serotonin in health and disease

P De Deurwaerdère, G Di Giovanni - International journal of molecular …, 2020 - mdpi.com
… mysterious functions of serotonin (5-hydroxytryptamine; 5-HT)… An interesting emphasis on
the early 5-HT mechanisms … mainly due to the reuptake by the SERT among the functions of 5-…

Exploring the role of serotonin as an immune modulatory component in cardiovascular diseases

A Imamdin, EPC van der Vorst - International Journal of Molecular …, 2023 - mdpi.com
… a role in the functioning of the cardiovascular system due to its … serotonin transporter (SERT)
channels, which are membrane … and T cell proliferation by 5-hydroxytryptamine. J. Immunol. …

Transporter-dependent uptake and metabolism of myocardial interstitial serotonin in the rat heart

T Sonobe, T Akiyama, JT Pearson - The Journal of Physiological Sciences, 2022 - Springer
… Myocardial interstitial serotonin (5-hydroxytryptamine, 5-HT) … In the heart, serotonin
transporter (SERT) exists on the … Platelets might concentrate 5-HT to the vesicle and reuse 5-HT. …

The role of serotonin neurotransmission in gastrointestinal tract and pharmacotherapy

T Guzel, D Mirowska-Guzel - Molecules, 2022 - mdpi.com
5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter … the serotonin reuptake
transporter (SERT) or organic cation … is present in the CNS, cardiovascular system, and GI tract. …

[图书][B] The Role of Serotonin in Atherosclerosis

YJ Seibel - 2020 - search.proquest.com
… correct name of serotonin is 5-hydroxytryptamine (5-HT). … This transport is mediated by a
serotonin transporter (SERT or 5… they get transported through the vascular system and have a …

Serotonin Receptors in Myocardial Infarction: Friend or Foe?

FS Bahr, M Ricke-Hoch, E Ponimaskin… - ACS Chemical …, 2024 - ACS Publications
focuses on the signaling pathways of the serotonin receptors 1, 2, 4, and 7, which are expressed
in the cardiovascular system, during disease … The serotonin transporters (5-HTT or SERT

5-HT Disease

JC Snider, WD Merryman - 5-HT2B Receptors: From Molecular …, 2021 - books.google.com
… 5-HT2BR antagonist SERT Serotonin transporter SHR … unique roles for serotonin—or 5-hydroxytryptamine
(5-HT)—… Increased plasma 5-HT level leads to carcinoid heart disease