Midbrain dopamine (DA) and serotonin (5-HT) neurons regulate motivated behaviors,
including feeding, but less is known about how these circuits may interact. In this study, we
found that DA neurons in the mouse ventral tegmental area bidirectionally regulate the
activity of 5-HT neurons in the dorsal raphe nucleus (DRN), with weaker stimulation causing
DRD2-dependent inhibition and overeating, while stronger stimulation causing DRD1-
dependent activation and anorexia. Furthermore, in the activity-based anorexia (ABA) …

Reports an error in" A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons
causes anorexia in mice" by Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong
Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han,
Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He and Yong Xu
(Nature Neuroscience, 2022 [May], Vol 25 [5], 646-658). In the version of this article initially
published, the bar graph shown in Fig. 6d was a duplicate of Fig. 6c. The figure panel has …