Final results of a phase 1 study of loncastuximab tesirine in relapsed/refractory B-cell non-Hodgkin lymphoma

M Hamadani, J Radford, C Carlo-Stella… - Blood, The Journal …, 2021 - ashpublications.org
Loncastuximab tesirine (ADCT-402) is an antibody-drug … As demonstrated in this study,
loncastuximab tesirine has … A phase I study of ADCT-402 (loncastuximab tesirine), a novel

Loncastuximab tesirine for treatment of relapsed or refractory diffuse large B cell lymphoma

K Goparaju, PF Caimi - Expert Opinion on Biological Therapy, 2021 - Taylor & Francis
… , phase II trial included 145 patients with relapsed/ refractory … has been observed with
ADCT-402 [Citation57], study of other … Loncastuximab tesirine is an antibody drug conjugate that …

Loncastuximab tesirine: An effective therapy for relapsed or refractory diffuse large B-cell lymphoma

B Xu - European Journal of Clinical Pharmacology, 2022 - Springer
B-cell lymphoma, ADCT-402, antibodydrug conjugate, loncastuximab tesirine and non-Hodgkin's
lymphoma… -5 are positive, then the value of loncastuximab tesirine as a novel anti-R/R …

The antibody-drug conjugate loncastuximab tesirine for the treatment of diffuse large B-cell lymphoma

E Calabretta, M Hamadani, PL Zinzani… - Blood, The Journal …, 2022 - ashpublications.org
… subtype of non-Hodgkin lymphoma. Relapsed/refractory disease represents remains an …
of the anti-CD19 ADC ADCT-402 (loncastuximab tesirine) containing the PBD dimer payload …

Loncastuximab tesirine, an anti-CD19 antibody-drug conjugate, in relapsed/refractory B-cell acute lymphoblastic leukemia

N Jain, W Stock, A Zeidan, E Atallah… - Blood …, 2020 - ashpublications.org
Loncastuximab tesirine (also known as ADCT-402) is an … in non-Hodgkin lymphoma (NHL),
and a phase 2 trial has been … Loncastuximab tesirine is a novel CD19-targeted humanized …

Loncastuximab tesirine in relapsed or refractory diffuse large B-cell lymphoma: a review of clinical data

F Furqan, M Hamadani - Therapeutic Advances in …, 2022 - journals.sagepub.com
… its role in both frontline as well as relapsed refractory setting. … A phase I study of ADCT-402
(loncastuximab tesirine), a novel pyrrolobenzodiazepine-based antibody-drug conjugate, in …

Loncastuximab tesirine in relapsed or refractory diffuse large B-cell lymphoma (LOTIS-2): a multicentre, open-label, single-arm, phase 2 trial

PF Caimi, W Ai, JP Alderuccio, KM Ardeshna… - The Lancet …, 2021 - thelancet.com
… A phase I study of ADCT-402 (loncastuximab tesirine), a novel pyrrolobenzodiazepine-based
antibody-drug conjugate, in … in relapsed/refractory B-cell non-Hodgkin lymphoma. …

[HTML][HTML] … -CD19 monoclonal antibodies for the treatment of relapsed or refractory B-cell malignancies: A narrative review with focus on diffuse large B-cell lymphoma

PL Zinzani, G Minotti - Journal of cancer research and clinical oncology, 2022 - Springer
… [ADCT-402]) (Katz and Herishanu 2014; Narkhede and Tafasitamab … relapsed/refractory
setting in other forms of B-cell NHL. Like tafasitamab, loncastuximab tesirine has been studied in …

[PDF][PDF] Loncastuximab Tesirine: Structure, Mechanism and Clinical Trial

Y Sun - clausiuspress.com
… and phase II experimental studies in non-Hodgkin's lymphoma… means antibodies of
antibody-drug conjugate targeted binding … ADCT-402 is a good choice for relapsed/ refractory

The antiCD19 antibody drug immunoconjugate loncastuximab achieves responses in DLBCL relapsing after antiCD19 CAR-T cell therapy

PF Caimi, KM Ardeshna, E Reid, W Ai… - Clinical Lymphoma …, 2022 - Elsevier
… in relapsed/refractory B-cell non-Hodgkin lymphoma … initial results of a phase 2 study
of loncastuximab tesirine, a novel pyrrolobenzodiazepine-based antibody-drug conjugate