[HTML][HTML] Understanding post-angiogenic tumor growth: insights from vascular network properties in cellular automata modeling

JU Legaria-Peña, F Sánchez-Morales… - Chaos, Solitons & …, 2024 - Elsevier
vascular network properties are related to tumor growth and treatment outcomes in a …
cellular automata model for angiogenic cancer development. The model simulates tumor growth

Preclinical murine tumor models: a structural and functional perspective

MV Guerin, V Finisguerra, BJ Van den Eynde… - Elife, 2020 - elifesciences.org
… in murine tumor models often do not work in clinics. In a detailed comparison of transplanted
and spontaneous tumor models, we focus on structure–function relationships in the tumor

Vascularized cancer on a chip: The effect of perfusion on growth and drug delivery of tumor spheroid

Y Nashimoto, R Okada, S Hanada, Y Arima… - Biomaterials, 2020 - Elsevier
tumor spheroid consisting of only tumor cells has been widely used as a simple avascular
tumor model, heterotypic spheroid models … noncancerous cells into tumor microenvironments (…

Bioprinting of in vitro tumor models for personalized cancer treatment: a review

S Mao, Y Pang, T Liu, Y Shao, J He, H Yang… - …, 2020 - iopscience.iop.org
… is to present the development of bioprinted in vitro tumor models for personalized cancer …
the topological structure of the matrix on tumor growth. Ling et al [85]. have printed sacrificial …

Microengineered perfusable 3D-bioprinted glioblastoma model for in vivo mimicry of tumor microenvironment

L Neufeld, E Yeini, N Reisman, Y Shtilerman… - Science …, 2021 - science.org
… volumes compared to those of the control group 1 month following treatment initiation, tumor
growth inhibition in our fibrin 3D-bioink was observed in a shorter timeframe already after 1 …

Breast cancer models: Engineering the tumor microenvironment

G Bahcecioglu, G Basara, BW Ellis, X Ren, P Zorlutuna - Acta biomaterialia, 2020 - Elsevier
… /or genotype due to cellular mutations that results in uncontrolled cell division [3,4,23]. This
cellular growth then leads to further mutations and tumor development within the diseased …

Angiogenesis as a hallmark of solid tumors-clinical perspectives

J Majidpoor, K Mortezaee - Cellular Oncology, 2021 - Springer
… , causing reduction of vascular integrity, an increase in vessel immaturity, incoherent perfusion,
defective functionality and enhanced tumor dissemination and metastasis. The abnormal …

[PDF][PDF] Dual programmed death receptor‐1 and vascular endothelial growth factor receptor‐2 blockade promotes vascular normalization and enhances antitumor …

K Shigeta, M Datta, T Hato, S Kitahara, IX Chen… - …, 2020 - Wiley Online Library
… significantly delayed primary tumor growth but failed … model. However, dual anti-PD-1/
VEGFR-2 therapy significantly inhibited primary tumor growth and doubled survival in both models

Properties of the vascular networks in malignant tumors

JC Chimal-Eguía, E Castillo-Montiel… - Entropy, 2020 - mdpi.com
… To fully understand the behaviour of an organism, organ or even a single cell, we need to …
structure of tumors, and give us some insights into the mechanisms of tumor growth and …

[HTML][HTML] In vitro throughput screening of anticancer drugs using patient-derived cell lines cultured on vascularized three-dimensional stromal tissues

Y Takahashi, R Morimura, K Tsukamoto, S Gomi… - Acta Biomaterialia, 2024 - Elsevier
… a cancer-stromal tissue model in which cancer cells are placed above and inside stromal
tissue with vascular network structures derived from vascular endothelial cells in fibroblast …