… processes that govern the genesis of pancreatic cancer. These … Besides the key signaling
pathways that play pivotal roles in … play a crucial role in the initiation of pancreatic neoplasms, …

… as an oncogene in malignancies of pancreatic origin [13]. … suggests that pancreatic
desmoplastic protumor signaling is … does not play a significant role in the peptide phosphorylation …

… origin of PDAC and the possible transformation of normal stem cell compartment under the
oncogenic signaling and factors leading to the genesis … pattern and significant role of genes …

… Inhibitors that target MAPK signaling will increase PD-L1 and alter the tumor … A, KRAS plays
a central role in tumor development, regulating downstream proteins (RAF, MEK, and ERK) …

… modulation of the TME of pancreatic ductal adenocarcinoma (PDAC). … Thus, KRAS/CXCR2
signaling plays a major role in … It is noteworthy that PSCs represent a major origin of fibrosis …

… three key target genes of MALAT1, which include CCND1, RAF-… signaling pathway, pathways
in cancer, and the MAPK … MiRNAs play a significant role in the initiation and progression …

… in pancreatic cancer (KRAS, CDKN2A, TP53 and SMAD4), we summarise the significant role
of … collectively highlight the essential role of the RAF–MEK–ERK signalling pathway in the …

… Because the origin of the fibroblasts present in pathological conditions is … signals that
proceed through MAPK pathways in route to PMF activation is a testament to the central roles …

… of 140 pancreatic cancers, 67 normal adjacent tissues, and 9 normal pancreatic ductal
tissues. … of genomic alterations on protein expression, signaling pathways, and post-translational …

… that the MAPK signaling pathway is involved in the genesis of … of the oncogenic role of KRAS
in PDAC could lead to novel … The HER2/neu signaling pathway plays a key role in PDAC …