Advances in erlotinib delivery systems: Addressing challenges and exploring opportunities in EGFR-targeted cancer therapies
M Pourmadadi, V Mohammadzadeh… - Inorganic Chemistry …, 2024 - Elsevier
… the difficulty posed by erlotinib resistance. Delivery systems … bioavailability and solubility
of erlotinib, thereby potentially … the precise administration of erlotinib to particular malignant …
of erlotinib, thereby potentially … the precise administration of erlotinib to particular malignant …
QbD assisted development of inhalable spray-dried erlotinib procubosomal system for the effective management of non-small cell lung cancer
A Singh, V Rana - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
… The four experimental groups established for comparative studies were as follows: Group
I rats received a 10 mg/kg dose of pure ERL via oral delivery, Group II rats received the same …
I rats received a 10 mg/kg dose of pure ERL via oral delivery, Group II rats received the same …
[HTML][HTML] Effectiveness and safety of the bevacizumab and erlotinib combination versus erlotinib alone in EGFR mutant metastatic non-small-cell lung cancer …
R Motta-Guerrero, A Leon Garrido-Lecca… - Frontiers in …, 2024 - frontiersin.org
… and erlotinib, we searched databases including clinical trial randomized studies and reviews
… In conclusion, the study shows that the bevacizumab–erlotinib combination significantly …
… In conclusion, the study shows that the bevacizumab–erlotinib combination significantly …
[HTML][HTML] Oral squamous cell carcinoma cells with acquired resistance to erlotinib are sensitive to anti-cancer effect of quercetin via pyruvate kinase M2 (PKM2)
CY Chan, SC Hong, CM Chang, YH Chen, PC Liao… - Cells, 2023 - mdpi.com
… study, we aimed to unveil key intracellular molecules and adjuvant reagents to overcome
erlotinib … In conclusion, our data support the application of quercetin in anti-erlotinib-resistant …
erlotinib … In conclusion, our data support the application of quercetin in anti-erlotinib-resistant …
Dual stimuli-responsive release of aptamer AS1411 decorated erlotinib loaded chitosan nanoparticles for non-small-cell lung carcinoma therapy
K Saravanakumar, A Sathiyaseelan… - Carbohydrate …, 2020 - Elsevier
… However, there is no report on application of aptamer-tagged Erlotinib loaded chitosan
nanoparticles. Hence the present study was to develop the DDS using the dual stimuli-…
nanoparticles. Hence the present study was to develop the DDS using the dual stimuli-…
… liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib
… erlotinib formation: We studied … Erlotinib and resveratrol concentration in our study were
chosen based on previous in vitro experiments that studied the effect of resveratrol on erlotinib …
chosen based on previous in vitro experiments that studied the effect of resveratrol on erlotinib …
[HTML][HTML] Early [18] FDG PET/CT scan predicts tumor response in head and neck squamous cell cancer patients treated with erlotinib adjusted per smoking status
M Porosnicu, A O'Brien Cox, JD Waltonen… - Frontiers in …, 2022 - frontiersin.org
… erlotinib among patients with HNSCC. For the first time, this study shows that an increased
erlotinib … 150 mg in non-smokers, with increased study-specific defined tumor response. The …
erlotinib … 150 mg in non-smokers, with increased study-specific defined tumor response. The …
PEGylated erlotinib HCl injectable nanoformulation for improved bioavailability
H Bhargave, H Nijhawan, KS Yadav - AAPS PharmSciTech, 2023 - Springer
… An in vitro drug release study was performed in order to determine the release behavior of
the Erlotinib HCl from nanoparticles. For this study, freeze-dried nanoparticles of Erlotinib HCl …
the Erlotinib HCl from nanoparticles. For this study, freeze-dried nanoparticles of Erlotinib HCl …
An application of quality by design and analytical greenness assessment approach for the development of erlotinib stability indicating method
… Erlotinib (ERL) is a tyrosine kinase inhibitor associated with the epidermal growth factor
receptor (EGFR) containing susceptible functional groups such as quinazoline and amine ketone…
receptor (EGFR) containing susceptible functional groups such as quinazoline and amine ketone…
The lack of head-to-head randomised trials and the consequences for patients and national health service: The case of non-small cell lung cancer
R Lasala, A Romagnoli, F Santoleri, V Isgrò… - European Journal of …, 2024 - Springer
… studies between the latest generation of drugs. Consequently, ambiguous areas exist due to
the lack of comparative studies … Additionally, the BEVERLY study aimed to study the erlotinib…
the lack of comparative studies … Additionally, the BEVERLY study aimed to study the erlotinib…